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3hqc
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hqc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hqc RCSB], [http://www.ebi.ac.uk/pdbsum/3hqc PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/3hqc TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hqc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hqc RCSB], [http://www.ebi.ac.uk/pdbsum/3hqc PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/3hqc TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TENC1_HUMAN TENC1_HUMAN]] Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling.<ref>PMID:15817639</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 19:10, 24 December 2014
Crystal structure of Phosphotyrosine-binding domain from the Human Tensin-like C1 domain-containing phosphatase (TENC1)
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Categories: Homo sapiens | Atwell, S | Bain, K | Burley, S K | Dickey, M | Do, J | Gheyi, T | Klemke, R | Structural genomic | Romero, R | Sampathkumar, P | Sauder, J M | Wasserman, S | Cell junction | Cell membrane | Human tensin-like c1 domain-containing phosphatase | Hydrolase | Kiaa1075 | Membrane | Metal-binding | NYSGXRC, New York SGX Research Center for Structural Genomics | Phorbol-ester binding | Phosphoprotein | Phosphotyrosine binding domain | Protein phosphatase | PSI, Protein structure initiative | Ptb | Sh2 domain | Tenc1 | Tns2 | Zinc-finger
