3dgq
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dgq RCSB], [http://www.ebi.ac.uk/pdbsum/3dgq PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dgq RCSB], [http://www.ebi.ac.uk/pdbsum/3dgq PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GSTP1_HUMAN GSTP1_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.<ref>PMID:21668448</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 13:42, 25 December 2014
Crystal structure of the glutathione transferase PI enzyme in complex with the bifunctional inhibitor, etharapta
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