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3deb
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3deb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3deb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3deb RCSB], [http://www.ebi.ac.uk/pdbsum/3deb PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3deb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3deb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3deb RCSB], [http://www.ebi.ac.uk/pdbsum/3deb PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BXC1_CLOBO BXC1_CLOBO]] Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves syntaxin. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 21:04, 24 December 2014
Crystal Structure of apo form (Zinc removed) of the Botulinum Neurotoxin Type C Light Chain
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Categories: Bontoxilysin | Clostridium botulinum | Kumaran, D | Rawat, R | Swaminathan, S | Apo form | Botulinum neurotoxin | Botulism | Hydrolase | Light chain | Membrane | Metal-binding | Metalloprotease | Neurotoxin | Protease | Secreted | Snare protein | Toxin | Transmembrane
