3dav
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dav OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dav RCSB], [http://www.ebi.ac.uk/pdbsum/3dav PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dav OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dav RCSB], [http://www.ebi.ac.uk/pdbsum/3dav PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PROF_SCHPO PROF_SCHPO]] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. In S.pombe, it is essential for cytokinesis. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 22:36, 24 December 2014
Schizosaccharomyces Pombe Profilin crystallized from Sodium formate
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