Acyl-CoA dehydrogenase
From Proteopedia
(Difference between revisions)
| Line 44: | Line 44: | ||
**[[3oib]] - ACHD + FAD – ''Mycobacterium smegmatis''<br /> | **[[3oib]] - ACHD + FAD – ''Mycobacterium smegmatis''<br /> | ||
**[[4m9a]] – ACDH + FAD – ''Burkholderia thailandensis''<br /> | **[[4m9a]] – ACDH + FAD – ''Burkholderia thailandensis''<br /> | ||
| - | **[[3owa]] - ACDH + FAD – ''Bacillus anthracis'' | + | **[[3owa]] - ACDH + FAD – ''Bacillus anthracis''<br /> |
| + | **[[4rm7]] – ShACDH – ''Slackia heliotrinireducens''<br /> | ||
| + | **[[4w9u]] – ACDH – ''Brucella abortus''<br /> | ||
| + | |||
| + | *Butyryl-CoA dehydrogenase | ||
| + | |||
| + | **[[4u83]] – ShBCDH <br /> | ||
| + | **[[1buc]] – BCDH + acetoacetyl-CoA + FAD – ''Megasphaera elsdenii''<br /> | ||
| + | **[[1rx0]] – hiso-BCDH + methacrylyl-CoA + FAD <br /> | ||
| + | |||
| + | |||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 08:55, 22 January 2015
Acyl-CoA dehydrogenase (ACDH) catalyzes the introduction of a double bond between C2 and C3 of the thio-ester CoA substrate. This is the first reaction in fatty acid metabolism which produces acetyl-CoA. FAD is the cofactor of ACDH activity. ACDH is classified according to the length of its substrates as short- (SCAD), medium- (MCAD), very- and very long-chain (VLCAD) ACDH. Impairment of the activity of ACDH causes a variety of diseases associated with lack of fatty acid metabolism.
3D structures of acyl-CoA dehydrogenase
Updated on 22-January-2015
