Adenosine deaminase
From Proteopedia
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'''Adenosine deaminase''' (ADA) deaminates adenosine and deoxyadenosine into inosine or deoxyinosine. ADA is part of the purine metabolism. In humans ADA is involved in the development and maintenance of the immune system. ADA deficiency is the cause of severe combined immunodeficiency (SCID). SCID was the first disorder to be treated by gene therapy. There are 2 isoforms of ADA: ADA1 and ADA2. ADA contains Zn+2 ion in its active site. | '''Adenosine deaminase''' (ADA) deaminates adenosine and deoxyadenosine into inosine or deoxyinosine. ADA is part of the purine metabolism. In humans ADA is involved in the development and maintenance of the immune system. ADA deficiency is the cause of severe combined immunodeficiency (SCID). SCID was the first disorder to be treated by gene therapy. There are 2 isoforms of ADA: ADA1 and ADA2. ADA contains Zn+2 ion in its active site. | ||
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== 3D Structures of adenosine deaminase == | == 3D Structures of adenosine deaminase == |
Revision as of 11:12, 12 November 2014
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3D Structures of adenosine deaminase
Updated on 12-November-2014