Aldose Reductase
From Proteopedia
(Difference between revisions)
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**[[3v9q]] - hAldR+NADP+ phenol derivative<br /> | **[[3v9q]] - hAldR+NADP+ phenol derivative<br /> | ||
**[[3rx2]], [[3rx3]], [[3rx4]], [[3s3g]] - hAldR+NADP+ sulindac inhibitor<br /> | **[[3rx2]], [[3rx3]], [[3rx4]], [[3s3g]] - hAldR+NADP+ sulindac inhibitor<br /> | ||
| + | **[[4igs]] - hAldR+NADP+ polyfluorinated inhibitor<br /> | ||
| + | **[[4lau]], [[4laz]], [[4lb3]], [[4lb4]], [[4lbr]], [[4lbs]] - hAldR+NADP+ carbamoyl inhibitor<br /> | ||
**[[3fx4]] – pAldR+NADP+thiazolidine derivative <br /> | **[[3fx4]] – pAldR+NADP+thiazolidine derivative <br /> | ||
**[[3h4g]] – pAldR+NADP+fidarestat<br /> | **[[3h4g]] – pAldR+NADP+fidarestat<br /> | ||
Revision as of 10:30, 28 January 2015
Aldose Reductase (AldR) is an NADPH-dependent enzyme which reduces aldehydes and carbonyls. It reduces glucose to sorbitol in the glucose metabolism pathway. The AldR is implicated in diabetics and causing Iodine Deficiency Disorder (IDD) and its treatment involves the use of IDD inhibitors of AldR.
3D Structures of Aldose Reductase
Updated on 28-January-2015
