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4pbv
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbv RCSB], [http://www.ebi.ac.uk/pdbsum/4pbv PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbv RCSB], [http://www.ebi.ac.uk/pdbsum/4pbv PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NTRK3_CHICK NTRK3_CHICK]] Receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase and PLCG1. The KT and KD isoforms fail to stimulate transformation, process outgrowth or survival. Isoform KI25 exhibits tyrosine phosphorylation in the absence of ligand and is unable to mediate survival of neuronal cells. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 18:15, 24 December 2014
Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC
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