1l6h
From Proteopedia
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|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
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| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l6h OCA], [http://www.ebi.ac.uk/pdbsum/1l6h PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1l6h RCSB]</span> | ||
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[[Category: plant ltp]] | [[Category: plant ltp]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:58:43 2008'' |
Revision as of 18:58, 30 March 2008
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Solution Structure of Plant nsLTP2 purified from Rice (oryza Sativa)
Overview
The three-dimensional structure of rice nonspecific lipid transfer protein (nsLTP2) has been solved for the first time. The structure of nsLTP2 was obtained using 813 distance constraints, 30 hydrogen bond constraints, and 19 dihedral angle constraints. Fifteen of the 50 random simulated annealing structures satisfied all of the constraints and possessed good nonbonded contacts. The novel three-dimensional fold of rice nsLTP2 contains a triangular hydrophobic cavity formed by three prominent helices. The four disulfide bonds required for stabilization of the nsLTP2 structure show a different pattern of cysteine pairing compared with nsLTP1. The C terminus of the protein is very flexible and forms a cap over the hydrophobic cavity. Molecular modeling studies suggested that the hydrophobic cavity could accommodate large molecules with rigid structures, such as sterols. The positively charged residues on the molecular surface of nsLTP2 are structurally similar to other plant defense proteins.
About this Structure
1L6H is a Single protein structure of sequence from Oryza sativa. Full crystallographic information is available from OCA.
Reference
Solution structure of plant nonspecific lipid transfer protein-2 from rice (Oryza sativa)., Samuel D, Liu YJ, Cheng CS, Lyu PC, J Biol Chem. 2002 Sep 20;277(38):35267-73. Epub 2002 May 13. PMID:12011089
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