3e16
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e16 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3e16 RCSB], [http://www.ebi.ac.uk/pdbsum/3e16 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e16 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3e16 RCSB], [http://www.ebi.ac.uk/pdbsum/3e16 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PRSS8_HUMAN PRSS8_HUMAN]] Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).<ref>PMID:15246975</ref> <ref>PMID:15474520</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 21:46, 25 December 2014
X-ray structure of human prostasin in complex with Benzoxazole warhead peptidomimic, lysine in P3
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Categories: Homo sapiens | Harris, J L | Hornsby, M | Lesley, S A | Shipway, A | Spraggon, G | Benzoxazole | Cell membrane | Channel activating protease | Enac | Glycoprotein | Hcap-1 | Hydrolase | Inhibitor | Membrane | Prostasin | Protease | Secreted | Serine protease | Transmembrane | Zymogen
