CD8
From Proteopedia
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| - | <StructureSection load='3b9k' size='350' side='right' caption='Structure of CD8α ( | + | <StructureSection load='3b9k' size='350' side='right' caption='Structure of CD8α (magenta) and CD8β (green) complex with antibody heavy chain (cyan) and light chain (salmon) (PDB entry [[3b9k]])' scene='55/551462/Cv/1'> |
'''CD8''' (or '''Cluster of Differentiation 8''') is a T-cell co-receptor. CD8 binds to class I MHC protein. CD8 exists as 2 isoforms: α and β. CD8 forms a dimer of CD8α and CD8β. The extracellular domain of CD8 has immunoglobulin variable-like conformation. This domain of CD8α interacts with α3 domain of class I MHC enhancing the binding of the T-cell receptor and the target cell. | '''CD8''' (or '''Cluster of Differentiation 8''') is a T-cell co-receptor. CD8 binds to class I MHC protein. CD8 exists as 2 isoforms: α and β. CD8 forms a dimer of CD8α and CD8β. The extracellular domain of CD8 has immunoglobulin variable-like conformation. This domain of CD8α interacts with α3 domain of class I MHC enhancing the binding of the T-cell receptor and the target cell. | ||
Revision as of 12:21, 24 November 2015
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3D Structures of CD8
Updated on 24-November-2015
