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Exosome
From Proteopedia
(Difference between revisions)
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== Function == | == Function == | ||
<scene name='60/609824/2nn6/8'>Exosome</scene> | <scene name='60/609824/2nn6/8'>Exosome</scene> | ||
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| + | '''Enzymatic function''' | ||
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| + | The exosome is primarily a 3'-5' exoribonuclease, meaning that it degrades RNA molecules from their 3' end. In eukaryotes it also have an endoribonucleolytic function, meaning it cleaves RNA at sites within the molecule. | ||
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| + | '''Substrates''' | ||
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| + | The exosome is involved in the degradation and processing of a wide variety of RNA species. Substrates of the exosome include messenger RNA, ribosomal RNA, and many species of small RNAs. | ||
== Disease == | == Disease == | ||
'''Autoimmunity''' | '''Autoimmunity''' | ||
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== Structural highlights == | == Structural highlights == | ||
| - | The core of the Exosom complex is made of a ring, which consisting of six RNases proteins (Rnase PH-like proteins). | + | The core of the Exosom complex is made of a ring, which is consisting of six RNases proteins (Rnase PH-like proteins), and other proteins are attached. |
<scene name="/12/3456/Sample/1">1</scene><scene name="/12/3456/Sample/2">2</scene> | <scene name="/12/3456/Sample/1">1</scene><scene name="/12/3456/Sample/2">2</scene> | ||
Revision as of 08:15, 22 November 2014
Exosome
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