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Dehalogenase

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Line 30: Line 30:
**[[1hde]], [[1be0]], [[1bee]], [[1bez]] – XaHDH (mutant)<br />
**[[1hde]], [[1be0]], [[1bee]], [[1bez]] – XaHDH (mutant)<br />
**[[1bn6]], [[1bn7]], [[4kaa]], [[4kac]], [[4kaf]] – RrHDH – ''Rhodococcus rhodochrous'' <br />
**[[1bn6]], [[1bn7]], [[4kaa]], [[4kac]], [[4kaf]] – RrHDH – ''Rhodococcus rhodochrous'' <br />
-
**[[2v9z]] – RrHDH (mutant) <br />
+
**[[2v9z]], [[4wcv]] – RrHDH (mutant) <br />
**[[1cv2]] – SpHDH – ''Sphingomonas paucimobilis''<br />
**[[1cv2]] – SpHDH – ''Sphingomonas paucimobilis''<br />
**[[4h77]] – SphHDH – ''Sphignobium''<br />
**[[4h77]] – SphHDH – ''Sphignobium''<br />
-
**[[4h7d]] – SphHDH (mutant)<br />
+
**[[4h7d]], [[4h7k]] – SphHDH (mutant)<br />
 +
**[[2xt0]] – HDH – ''Plesiocystis pacifica''<br />
 +
**[[3wi7]] – AtHDH – ''Agrobacterium tumefaciens''<br />
 +
**[[3wib]] – AtHHDH (mutant)<br />
*''Haloalkane dehalogenase complex with halide ion''
*''Haloalkane dehalogenase complex with halide ion''
**[[1edb]], [[1edd]], [[2eda]], [[2edc]], [[2dhe]], [[1b6g]] – XaHDH + halide<br />
**[[1edb]], [[1edd]], [[2eda]], [[2edc]], [[2dhe]], [[1b6g]] – XaHDH + halide<br />
-
**[[1cij]] – XaHDH (mutant) + halide<br />
+
**[[1cij]] – XaHDH (mutant) + Br<br />
**[[1d07]], [[1iz7]], [[1k5p]], [[1mj5]] – SpHDH + halide <br />
**[[1d07]], [[1iz7]], [[1k5p]], [[1mj5]] – SpHDH + halide <br />
**[[3fbw]], [[1cqw]], [[4hzg]] – RrHDH + halide <br />
**[[3fbw]], [[1cqw]], [[4hzg]] – RrHDH + halide <br />
-
**[[3a2m]], [[3a2n]], [[3afi]] – BjHDH + halide – ''Bradyrhizobium japonicum''<br />
+
**[[3a2m]], [[3a2n]], [[3afi]] – BjHDH + Cl – ''Bradyrhizobium japonicum''<br />
-
**[[3a2l]] – BjHDH (mutant) + halide <br />
+
**[[3a2l]] – BjHDH (mutant) + Cl <br />
-
**[[4k2a]] – HDH + halide – ''Bradyrhizobium elkanii''<br />
+
**[[4k2a]] – HDH + Cl – ''Bradyrhizobium elkanii''<br />
**[[3rk4]], [[3sk0]], [[4f5z]], [[4f60]] – RrHDH (mutant) + halide <br />
**[[3rk4]], [[3sk0]], [[4f5z]], [[4f60]] – RrHDH (mutant) + halide <br />
**[[4h7e]], [[4h7f]], [[4h7h]], [[4h7i]], [[4h7j]] [[4h7k]] – SphHDH (mutant) + halide <br />
**[[4h7e]], [[4h7f]], [[4h7h]], [[4h7i]], [[4h7j]] [[4h7k]] – SphHDH (mutant) + halide <br />
-
**[[4brz]] – RhHDH + halide - ''Rhodobacteraceae''<br />
+
**[[4brz]] – RhHDH + Cl - ''Rhodobacteraceae''<br />
 +
**[[4mj3]] – HDH + Cl – ''Mycobacterium rhodesiae''<br />
*''Haloalkane dehalogenase other complexes''
*''Haloalkane dehalogenase other complexes''
Line 62: Line 66:
**[[1k63]] – SpHDH + bromopropene-1-ol + Cl + Br<br />
**[[1k63]] – SpHDH + bromopropene-1-ol + Cl + Br<br />
**[[4fwb]] – SpHDH (mutant) + trichloropropane + Cl<br />
**[[4fwb]] – SpHDH (mutant) + trichloropropane + Cl<br />
 +
**[[2o2h]] – MtHDH 3 + dichloroethane + Cl – ''Mycobacterium tuberculosis''<br />
 +
**[[2o2i]] – MtHDH 3 + propanediol + Br<br />
 +
**[[2qvb]] – MtHDH 3 + ethanediol + Cl<br />
 +
 +
* Haloalcohol dehalogenase complexes
 +
 +
**[[1zmt]] – AtHDH + p-nitrostyrene oxide <br />
*Fluoroacetate dehalogenase (FDH)
*Fluoroacetate dehalogenase (FDH)
Line 80: Line 91:
**[[1zmo]] – HHDH – ''Anthrobacter''<br />
**[[1zmo]] – HHDH – ''Anthrobacter''<br />
-
**[[3zn2]] – AtHHDH – ''Agrobacterium tumefaciens''<br />
+
**[[3zn2]] – AtHHDH <br />
*''Halohydrin dehalogenase complexes''
*''Halohydrin dehalogenase complexes''
Line 87: Line 98:
**[[1px0]] – AtHHDH + haloalcohol mimic<br />
**[[1px0]] – AtHHDH + haloalcohol mimic<br />
**[[1zo8]] – AtHHDH + p-nitrostyrene oxide<br />
**[[1zo8]] – AtHHDH + p-nitrostyrene oxide<br />
 +
**[[1pwz]] – AtHHDH + styrene oxide + Cl<br />
**[[4ixt]] – AtHHDH (mutant) + ethyl cyano-hydroxybutyrate<br />
**[[4ixt]] – AtHHDH (mutant) + ethyl cyano-hydroxybutyrate<br />
**[[4ixw]] – RrHHDH (mutant) + ethyl oxiranyl acetate – ''Rhizobium radiobacter''<br />
**[[4ixw]] – RrHHDH (mutant) + ethyl oxiranyl acetate – ''Rhizobium radiobacter''<br />
Line 95: Line 107:
**[[1jud]] – PsLHDH – ''Pseudomonas''<br />
**[[1jud]] – PsLHDH – ''Pseudomonas''<br />
**[[2w43]] – StLHDH – ''Sulfolobus tokodaii''<br />
**[[2w43]] – StLHDH – ''Sulfolobus tokodaii''<br />
 +
**[[2yml]], [[2ymm]], [[2ymp]], [[2ymq]] – RhLHDH <br />
 +
**[[4ce6]], [[4cf3]], [[4cf4]], [[4cf5]], [[4cnq]] – RhLHDH (mutant)<br />
 +
**[[3bjx]] – LHDH – ''Pseudomonas putida'' <br />
 +
**[[3umc]] – LHDH – ''Pseudomonas aeruginosa'' <br />
 +
**[[3um9]] – LHDH – ''Polaromonas'' <br />
 +
**[[3umg]] – LHDH – ''Rhodococcus jostii'' <br />
*''L-2-haloacid dehalogenase complexes''
*''L-2-haloacid dehalogenase complexes''
Line 104: Line 122:
**[[2w11]] – StLHDH + lactic acid <br />
**[[2w11]] – StLHDH + lactic acid <br />
**[[1qq6]], [[1qq7]] – XaLHDH + aspartate carboxymethyl ester + Cl<br />
**[[1qq6]], [[1qq7]] – XaLHDH + aspartate carboxymethyl ester + Cl<br />
 +
**[[2yn4]] – RhLHDH + chlorobutyrate<br />
*DL-2-haloacid dehalogenase (DLHDH)
*DL-2-haloacid dehalogenase (DLHDH)
Line 109: Line 128:
**[[4n2x]] – MeDLHDH – ''Methylobacterium''<br />
**[[4n2x]] – MeDLHDH – ''Methylobacterium''<br />
**[[3wj8]] – MeDLHDH + bromo-methylpropionate <br />
**[[3wj8]] – MeDLHDH + bromo-methylpropionate <br />
 +
 +
* S-2-haloacid dehalogenase (SHDH)
 +
 +
**[[2no4]] – BcSHDH IVA – ''Burkholderia cepacia''<br />
 +
**[[2no5]] – BcSHDH IVA + 2-monochloroprapanate<br />
*Iodotyrosine dehalogenase (ITDH)
*Iodotyrosine dehalogenase (ITDH)
Line 117: Line 141:
**[[3tnz]] – mITDH (mutant) + iodotyrosine<br />
**[[3tnz]] – mITDH (mutant) + iodotyrosine<br />
**[[3gh8]] – mITDH + diiodotyrosine<br />
**[[3gh8]] – mITDH + diiodotyrosine<br />
 +
**[[4ttb]] – hITDH 1 + FMN<br />
 +
**[[4ttc]] – hITDH 1 + FMN + iodotyrosine <br />
*cis-3-chloroacrylic acid dehalogenase (CaaD)
*cis-3-chloroacrylic acid dehalogenase (CaaD)
Line 139: Line 165:
**[[1nzy]] – PsCBCD <br />
**[[1nzy]] – PsCBCD <br />
**[[1jxz]] – PsCBCD + hydroxybenzoyl CoA <br />
**[[1jxz]] – PsCBCD + hydroxybenzoyl CoA <br />
 +
 +
*Tetrachloroethene reductive dehalogenase (TCRD)
 +
 +
**[[4uqu]], [[4ur3]] – SmTCRD catalytic subunit – ''Sulfurospirillum multivorans''<br />
 +
**[[4ur0]] – SmTCRD catalytic subunit + trichloroethene<br />
 +
**[[4ur1]] – SmTCRD catalytic subunit + tribromoethene<br />
 +
**[[4ur2]] – SmTCRD catalytic subunit + iodide<br />
 +
}}
}}

Revision as of 11:15, 22 March 2015

Structure of haloalkane dehalogenase complex with I- ion (purple) (PDB code 2edc).

Drag the structure with the mouse to rotate

3D structures of dehalogenase

Updated on 22-March-2015


References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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