Hila Cohen/Test Page

The use of JSmol in Proteopedia ^[1] or to the article describing Jmol ^[2] to the rescue.

Avidin is a protein that’s bind Vitamin B7, .

The Avidin is produced in the ovary of some lay eggs animals, and it’s found in the white of the egg ^[3].

Structure

Avidin is a tetrameric protein, but here will be shown only two units of the whole structure just to simplify it.

The secondary structure of Each Avidin monomer combines (pink) and an 8 stranded antiparalle (turquoise). The tertiary structure of each monomer is beta-barrel ^[4].

Structural highlights

Because of the curved structure of the protein, it’s easier to see where the N terminal is begins and the C terminal ends with .

References

1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
3. ↑ Green NM. Avidin. Adv Protein Chem. 1975;29:85-133. doi: 10.1016/s0065-3233(08)60411-8. PMID:237414 doi:http://dx.doi.org/10.1016/s0065-3233(08)60411-8
4. ↑ Livnah O, Bayer EA, Wilchek M, Sussman JL. Three-dimensional structures of avidin and the avidin-biotin complex. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5076-80. PMID:8506353