Dioxygenase

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*Protocatechuate 3,4-dioxygenase (PCD)
*Protocatechuate 3,4-dioxygenase (PCD)
-
**[[2pcd]] – PpPCD α,β + Fe+3 – ''Pseudomonas putida''<br />
+
**[[2pcd]], [[4who]], [[4whp]] – PpPCD α,β + Fe+3 – ''Pseudomonas putida''<br />
**[[3pcd]], [[1ykk]], [[1ykm]], [[1yko]], [[3lkt]], [[3mfl]], [[3mi1]], [[3mv4]], [[3t63]] – PpPCD α,β (mutant) + Fe+3 <br />
**[[3pcd]], [[1ykk]], [[1ykm]], [[1yko]], [[3lkt]], [[3mfl]], [[3mi1]], [[3mv4]], [[3t63]] – PpPCD α,β (mutant) + Fe+3 <br />
**[[1eo2]], [[1eo9]], [[1eoa]], [[2bum]], [[2but]] – AcPCD α,β + Fe+3 - ''Acinetobacter''<br />
**[[1eo2]], [[1eo9]], [[1eoa]], [[2bum]], [[2but]] – AcPCD α,β + Fe+3 - ''Acinetobacter''<br />
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*''PCD complex with aromatic compound''
*''PCD complex with aromatic compound''
-
**[[3pcf]], [[3pch]], [[3pci]] – PpPCD α,β + Fe+3 + HB derivative<br />
+
**[[3pcf]], [[3pch]], [[3pci]], [[4whq]], [[4whr]], [[4whs]] – PpPCD α,β + Fe+3 + HB derivative<br />
**[[3pca]], [[3pcb]], [[3pcc]] – PpPCD α,β + Fe+3 + HB <br />
**[[3pca]], [[3pcb]], [[3pcc]] – PpPCD α,β + Fe+3 + HB <br />
**[[1ykl]], [[1ykn]], [[1ykp]], [[3lmx]], [[3mv6]] – PpPCD α,β (mutant) + Fe+3 + DHB<br />
**[[1ykl]], [[1ykn]], [[1ykp]], [[3lmx]], [[3mv6]] – PpPCD α,β (mutant) + Fe+3 + DHB<br />
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**[[4ie4]], [[4ie6]] – hFto + Zn+2 + quinoline derivative<br />
**[[4ie4]], [[4ie6]] – hFto + Zn+2 + quinoline derivative<br />
**[[4ie7]] – hFto + Zn+2 + rhein<br />
**[[4ie7]] – hFto + Zn+2 + rhein<br />
 +
**[[4qkn]] – hFto + Mn+2 + meclofenamic acid<br />
 +
**[[4cxw]], [[4cxx]], [[4cxy]] – hFto + Ni+2 + inhibitor<br />
*''Alkb complex with DNA''
*''Alkb complex with DNA''
-
**[[3rzm]], [[3rzl]], [[3rzh]], [[3rzg]], [[3btz]] – hAlkb (mutant) + DNA<br />
+
**[[3rzm]], [[3rzl]], [[3rzh]], [[3rzg]], [[3btz]], [[4mg2]], [[4mgt]] – hAlkb (mutant) + DNA<br />
**[[3h8x]], [[3h8r]], [[3h8o]], [[3bty]] – hAlkb (mutant) + DNA + inhibitor<br />
**[[3h8x]], [[3h8r]], [[3h8o]], [[3bty]] – hAlkb (mutant) + DNA + inhibitor<br />
**[[3btx]] – hAlkb (mutant) + Mg+2 + DNA <br />
**[[3btx]] – hAlkb (mutant) + Mg+2 + DNA <br />
**[[3i49]], [[3i2o]] – hAlkb + Fe+2 + oxoglutarate + DNA <br />
**[[3i49]], [[3i2o]] – hAlkb + Fe+2 + oxoglutarate + DNA <br />
 +
**[[4nid]] – hAlkb + Mn+2 + oxoglutarate + DNA <br />
 +
**[[4nig]], [[4nih]], [[4nii]] – hAlkb (mutant) + Mn+2 + oxoglutarate + DNA <br />
 +
**[[3o1s]] – hAlkb + DNA <br />
**[[3i3m]] – hAlkb + Mn+2 + oxoglutarate + DNA<br />
**[[3i3m]] – hAlkb + Mn+2 + oxoglutarate + DNA<br />
**[[3s5a]], [[3s57]], [[3rzk]], [[3rzj]], [[3buc]], [[3bu0]], [[3bkz]] – hAlkb (mutant) + Mn+2 + oxoglutarate + DNA<br />
**[[3s5a]], [[3s57]], [[3rzk]], [[3rzj]], [[3buc]], [[3bu0]], [[3bkz]] – hAlkb (mutant) + Mn+2 + oxoglutarate + DNA<br />
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**[[3khc]] – hAlkb (mutant) + Co+2 + oxoglutarate + DNA + inhibitor<br />
**[[3khc]] – hAlkb (mutant) + Co+2 + oxoglutarate + DNA + inhibitor<br />
**[[3o1v]], [[3o1u]], [[3o1t]], [[3t1s]] – hAlkb (mutant) + Fe+3 + succinate + DNA + inhibitor<br />
**[[3o1v]], [[3o1u]], [[3o1t]], [[3t1s]] – hAlkb (mutant) + Fe+3 + succinate + DNA + inhibitor<br />
 +
 +
*Leucoanthocyanidin dioxygenase (LACD)
 +
 +
**[[1gp5]], [[1gp6]] – AtLACD + dihydroquercetin – ''Arabidopsis thaliana'' <br />
 +
**[[2brt]] – AtLACD + naringenin <br />
*'''Dioxygenase extradiol family'''
*'''Dioxygenase extradiol family'''
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**[[2nw8]], [[2nw9]] – XcTDO + heme + Mn + tryptophan derivative<br />
**[[2nw8]], [[2nw9]] – XcTDO + heme + Mn + tryptophan derivative<br />
**[[2nox]] – CmTDO + heme – ''Cupriavidus metallidurans''<br />
**[[2nox]] – CmTDO + heme – ''Cupriavidus metallidurans''<br />
 +
**[[4pw8]] - hTDO + Co+2 <br />
*Cysteine dioxygenase type I (CysDO)
*Cysteine dioxygenase type I (CysDO)
-
**[[2gh2]], [[4ieo]], [[4iep]], [[4ieq]], [[4ier]], [[4ies]], [[4iet]], [[4ieu]], [[4iev]], [[4iew]], [[4iex]], [[4iey]], [[4iez]], [[4jtn]], [[4jto]], [[4kwj]], [[4kwk]], [[4kwl]] – rCysDO + Fe+2 – rat <br />
+
**[[2gh2]], [[4ieo]], [[4iep]], [[4ieq]], [[4ier]], [[4ies]], [[4iet]], [[4ieu]], [[4iev]], [[4iew]], [[4iex]], [[4iey]], [[4iez]], [[4jtn]], [[4jto]], [[4kwj]], [[4kwk]], [[4kwl]], [[2b5h]] – rCysDO + Fe+2 – rat <br />
 +
**[[4ubg]], [[4ubh]] – rCysDO (mutant) + Fe+2 <br />
**[[3eln]] – rCysDO + Fe+2 + cysteine derivative<br />
**[[3eln]] – rCysDO + Fe+2 + cysteine derivative<br />
-
**[[2q4s]] – mCysDO + Ni+2 <br />
+
**[[2q4s]], [[2atf]] – mCysDO + Ni+2 <br />
**[[2ic1]] – hCysDO + Fe+2 + cysteine<br />
**[[2ic1]] – hCysDO + Fe+2 + cysteine<br />
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**[[1cjx]] – HPPD + Fe+2 – ''Pseudomonas fluorescens''<br />
**[[1cjx]] – HPPD + Fe+2 – ''Pseudomonas fluorescens''<br />
**[[1t47]] – HPPD + Fe+2 – ''Streptomyces avermitilis''<br />
**[[1t47]] – HPPD + Fe+2 – ''Streptomyces avermitilis''<br />
-
**[[1sqd]], [[1sp9]] – AtHPPD + Fe+3 – ''Arabidopsis thaliana''<br />
+
**[[3zgj]] – HPPD + Co+2 + mandelic acid – ''Streptomyces coelicolor''<br />
 +
**[[1sqd]], [[1sp9]] – AtHPPD + Fe+3 <br />
**[[1sqi]] – HPPD + Fe+3 + inhibitor - rat<br />
**[[1sqi]] – HPPD + Fe+3 + inhibitor - rat<br />
**[[1tfz]], [[1tg5]] – AtHPPD + Fe+3 + inhibitor <br />
**[[1tfz]], [[1tg5]] – AtHPPD + Fe+3 + inhibitor <br />
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**[[3r1j]] – HAD + Fe+3 – ''Mycobacterium avium''<br />
**[[3r1j]] – HAD + Fe+3 – ''Mycobacterium avium''<br />
**[[4j5i]] – HAD + Fe+3 – ''Mycobacterium smegmatis''<br />
**[[4j5i]] – HAD + Fe+3 – ''Mycobacterium smegmatis''<br />
 +
**[[3swt]] – HAD + Fe+3 – ''Mycobacterium marinum''<br />
*3-hydroxyanthranilate 3,4-dioxygenase (HAD)
*3-hydroxyanthranilate 3,4-dioxygenase (HAD)
-
**[[1yfu]] – CmHAD + Fe+3<br />
+
**[[1yfu]], [[4hvq]], [[4hvr]], [[4i3p]] – CmHAD + Fe+3<br />
 +
**[[4hvo]] – CmHAD + Fe+3 + Cu+2<br />
**[[1yfw]] – CmHAD + Fe+3 + O2 + hydroxyanthranilate<br />
**[[1yfw]] – CmHAD + Fe+3 + O2 + hydroxyanthranilate<br />
**[[1yfx]] – CmHAD + Fe+3 + NO + hydroxyanthranilate<br />
**[[1yfx]] – CmHAD + Fe+3 + NO + hydroxyanthranilate<br />
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*Carbazole 1,9a-dioxygenase (CDO)
*Carbazole 1,9a-dioxygenase (CDO)
-
**[[1vck]] – HAD ferredoxin component + Fe+3 + Fe2S2 – ''Pseudomonas resinovorans''<br />
+
**[[1vck]] – CDO ferredoxin component + Fe+3 + Fe2S2 – ''Pseudomonas resinovorans''<br />
-
**[[2de5]], [[2de6]] – JaHAD ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 – ''Janthinobacterium''<br />
+
**[[2de5]], [[2de6]] – JaCDO ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 – ''Janthinobacterium''<br />
-
**[[2de7]], [[3vmg]] – JaHAD ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 + carbazole<br />
+
**[[2de7]], [[3vmg]] – JaCDO ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 + carbazole<br />
-
**[[3vmh]] – JaHAD ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 + O2<br />
+
**[[3vmh]] – JaCDO ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 + O2<br />
-
**[[3vmi]] – JaHAD ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 + carbazole + O2<br />
+
**[[4nb8]], [[4nb9]], [[4nba]], [[4nbb]], [[4nbc]], [[4nbd]], [[4nbe]], [[4nbf]], [[4nbg]], [[4nbh]] – JaCDO ferredoxin and terminal oxygenase components (mutant) + Fe+2 + Fe2S2 <br />
 +
**[[3vmi]] – JaCDO ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 + carbazole + O2<br />
 +
**[[3gcf]] – CDO terminal oxygenase component + Fe+2 + Fe2S2 – ''Nocardioides aromaticivorans''<br />
 +
**[[3gkq]] – SpCDO terminal oxygenase component + Fe+2 + Fe2S2 <br />
*Homogentisate 1,2-dioxygenase (HGDO)
*Homogentisate 1,2-dioxygenase (HGDO)
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**[[4aq6]] – PpHGDO + Fe+3 + substrate<br />
**[[4aq6]] – PpHGDO + Fe+3 + substrate<br />
**[[3zds]] – PpHGDO + Fe+3 + O2<br />
**[[3zds]] – PpHGDO + Fe+3 + O2<br />
 +
 +
*Hydroxyethylphosphonate dioxygenase (PHPD)
 +
 +
**[[4yar]], [[3g7d]] – SvPHPD + Cd+2 – ''Streptomyces viridochromogenes''<br />
 +
**[[3rzz]] – SvPHPD (mutant) + Cd+2 <br />
 +
**[[3gbf]] – SvPHPD + Cd+2 + hydroxyethylphosphonate <br />
 +
 +
*Gallate dioxygenase (GD)
 +
 +
**[[3wrc]] – SpGD + Fe+2 + dehydroxybenzoate<br />
 +
**[[3wku]], [[3wpm]], [[3wr4]] – SpGD + Fe+3 + gallate<br />
 +
**[[3wr3]], [[3wr9]] – SpGD + Fe+2 + gallate<br />
 +
**[[3wrb]] – SpGD (mutant) + Fe+2 + gallate<br />
 +
**[[3wr8]], [[3wra]] – SpGD + Fe+2<br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:54, 24 March 2015

Structure of protocatechuate 3,4-dioxygenase with Fe+3 complex with dihydroxybenzoate (PDB entry 1eob)

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3D structures of Protocatechuate 3,4-dioxygenase

Updated on 24-March-2015

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky

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