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Estrogen-related receptor

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{{STRUCTURE_2gpv| PDB=2gpv | SIZE=400| SCENE= |right|CAPTION=Human estrogen-related receptor γ ligand-binding domain (cyan, grey, green, yellow, pink, purple) complex with nuclear receptor corepressor 2 peptide (dark red, orange) and 4-hydroxytamoxifen, [[2gpv]] }}
 
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<StructureSection load='2gpv' size='350' side='right' scene='' caption='Human estrogen-related receptor γ ligand-binding domain (cyan, grey, green, yellow, pink, purple) complex with nuclear receptor corepressor 2 peptide (dark red, orange) and 4-hydroxytamoxifen (PDB code [[2gpv]]) '>
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== Function ==
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'''Estrogen-related receptor''' (ERR) binds to estrogen response elements on DNA and modulates transcription in response to [[Hormone|hormone]]. ERR plays a role in energy homeostasis and cancer. There are 3 classes of ERR : ERRα, ERRβ and ERRγ.
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'''Estrogen-related receptor''' (ERR) binds to estrogen response elements on DNA and modulates transcription in response to [[Hormone|hormone]]. There are 3 classes of ERR : ERRα, ERRβ and ERRγ.
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== Relevance ==
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ERR plays a role in energy homeostasis and cancer.
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</StructureSection>
==3D structures of estrogen-related receptor==
==3D structures of estrogen-related receptor==
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**[[1vjb]] - mERR ligand-binding domain + 4-hydroxytamoxifen<br />
**[[1vjb]] - mERR ligand-binding domain + 4-hydroxytamoxifen<br />
}}
}}
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 14:59, 20 January 2016

Human estrogen-related receptor γ ligand-binding domain (cyan, grey, green, yellow, pink, purple) complex with nuclear receptor corepressor 2 peptide (dark red, orange) and 4-hydroxytamoxifen (PDB code 2gpv)

Drag the structure with the mouse to rotate

3D structures of estrogen-related receptor

Updated on 20-January-2016

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Wayne Decatur

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