Estrogen-related receptor
From Proteopedia
(Difference between revisions)
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| - | {{STRUCTURE_2gpv| PDB=2gpv | SIZE=400| SCENE= |right|CAPTION=Human estrogen-related receptor γ ligand-binding domain (cyan, grey, green, yellow, pink, purple) complex with nuclear receptor corepressor 2 peptide (dark red, orange) and 4-hydroxytamoxifen, [[2gpv]] }} | ||
| + | <StructureSection load='2gpv' size='350' side='right' scene='' caption='Human estrogen-related receptor γ ligand-binding domain (cyan, grey, green, yellow, pink, purple) complex with nuclear receptor corepressor 2 peptide (dark red, orange) and 4-hydroxytamoxifen (PDB code [[2gpv]]) '> | ||
| + | == Function == | ||
| - | '''Estrogen-related receptor''' (ERR) binds to estrogen response elements on DNA and modulates transcription in response to [[Hormone|hormone]] | + | '''Estrogen-related receptor''' (ERR) binds to estrogen response elements on DNA and modulates transcription in response to [[Hormone|hormone]]. There are 3 classes of ERR : ERRα, ERRβ and ERRγ. |
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| + | == Relevance == | ||
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| + | ERR plays a role in energy homeostasis and cancer. | ||
| + | </StructureSection> | ||
==3D structures of estrogen-related receptor== | ==3D structures of estrogen-related receptor== | ||
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**[[1vjb]] - mERR ligand-binding domain + 4-hydroxytamoxifen<br /> | **[[1vjb]] - mERR ligand-binding domain + 4-hydroxytamoxifen<br /> | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 14:59, 20 January 2016
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3D structures of estrogen-related receptor
Updated on 20-January-2016
