This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Farnesyl diphosphate synthase
From Proteopedia
(Difference between revisions)
| Line 26: | Line 26: | ||
**[[1yq7]], [[1yv5]], [[2f89]], [[2f8c]], [[2f92]], [[2f94]], [[2f9k]], [[2rah]], [[2opn]], [[2vf6]], [[3b7l]], [[2opm]], [[3n1v]], [[3n1w]], [[3n3l]], [[3n45]], [[3n46]], [[3n49]], [[3n5j]], [[3n6k]], [[3n5h]], [[4dem]], [[4ga3]], [[4jvj]] - hFPS + inhibitor<br /> | **[[1yq7]], [[1yv5]], [[2f89]], [[2f8c]], [[2f92]], [[2f94]], [[2f9k]], [[2rah]], [[2opn]], [[2vf6]], [[3b7l]], [[2opm]], [[3n1v]], [[3n1w]], [[3n3l]], [[3n45]], [[3n46]], [[3n49]], [[3n5j]], [[3n6k]], [[3n5h]], [[4dem]], [[4ga3]], [[4jvj]] - hFPS + inhibitor<br /> | ||
| - | **[[2qis]], [[3cp6]], [[3rye]], [[3s4j]] - hFPS (mutant) + inhibitor<br /> | + | **[[2qis]], [[3cp6]], [[3rye]], [[3s4j]], [[4n9u]] - hFPS (mutant) + inhibitor<br /> |
| + | **[[4kfa]], [[4kpj]], [[4kq5]] - hFPS (mutant) + osteoporosis drug<br /> | ||
| + | **[[4lpg]], [[4lph]], [[4n1z]], [[4p0x]] - hFPS + drug<br /> | ||
| + | **[[4nfi]], [[4nfj]], [[4nfk]], [[4qxs]] - hFPS + bisphosphonate<br /> | ||
| + | **[[4ng6]], [[4nke]], [[4nkf]], [[4nua]], [[4ogu]], [[4q23]] - hFPS (mutant) + bisphosphonate<br /> | ||
**[[2i19]], [[2ewg]], [[2ogd]], [[2p1c]], [[3dyg]], [[3dyh]], [[3efq]], [[3egt]] - TbFPS + inhibitor – ''Trypanosoma brucei''<br /> | **[[2i19]], [[2ewg]], [[2ogd]], [[2p1c]], [[3dyg]], [[3dyh]], [[3efq]], [[3egt]] - TbFPS + inhibitor – ''Trypanosoma brucei''<br /> | ||
**[[1ubw]], [[1ubx]] - cFPS (mutant) + GDP<br /> | **[[1ubw]], [[1ubx]] - cFPS (mutant) + GDP<br /> | ||
| Line 37: | Line 41: | ||
**[[2f8z]], [[4h5e]] - hFPS + IPP + inhibitor<br /> | **[[2f8z]], [[4h5e]] - hFPS + IPP + inhibitor<br /> | ||
| - | **[[4h5c]], [[4h3c]], [[4h5d]] - hFPS + phosphate + inhibitor<br /> | + | **[[4kpd]], [[4kqs]], [[4kqu]] - hFPS (mutant) + IPP + osteoporosis drug <br /> |
| + | **[[4p0v]], [[4p0w]] - hFPS + 2 drugs<br /> | ||
| + | **[[4h5c]], [[4h3c]], [[4h5d]], [[4lfv]] - hFPS + phosphate + inhibitor<br /> | ||
**[[1rqi]] – EcFPS + IPP + dimethylallyl S-thiolodiphosphate – ''Escherichia coli''<br /> | **[[1rqi]] – EcFPS + IPP + dimethylallyl S-thiolodiphosphate – ''Escherichia coli''<br /> | ||
**[[1rqj]] - EcFPS + IPP + inhibitor<br /> | **[[1rqj]] - EcFPS + IPP + inhibitor<br /> | ||
Revision as of 06:32, 2 April 2015
Farnesyl diphosphate synthase (FPS) also named farnesyl pyrophosphate synthase catalyzes the conversion of geranyl diphosphate (GDP) and isopentenyl diphosphate (IPP) to farnesyl diphosphate and diphosphate.
3D structures of farnesyl diphosphate synthase
Updated on 02-April-2015
Proteopedia Page Contributors and Editors (what is this?)
Hannah Campbell, Michal Harel, Tihitina Y Aytenfisu, Alexander Berchansky, Joel L. Sussman, Sandra B. Gabelli
