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1lrm

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|PDB= 1lrm |SIZE=350|CAPTION= <scene name='initialview01'>1lrm</scene>, resolution 2.1&Aring;
|PDB= 1lrm |SIZE=350|CAPTION= <scene name='initialview01'>1lrm</scene>, resolution 2.1&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene> and <scene name='pdbligand=HBI:7,8-DIHYDROBIOPTERIN'>HBI</scene>
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|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HBI:7,8-DIHYDROBIOPTERIN'>HBI</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span>
|GENE= PAH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= PAH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
 +
|DOMAIN=
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|RELATEDENTRY=[[1dmw|1DMW]], [[1j8u|1J8U]], [[1j8t|1J8T]], [[1pah|1PAH]], [[2pah|2PAH]], [[1kw0|1KW0]]
 +
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lrm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lrm OCA], [http://www.ebi.ac.uk/pdbsum/1lrm PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1lrm RCSB]</span>
}}
}}
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==Disease==
==Disease==
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Known diseases associated with this structure: Hyperphenylalaninemia, mild OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=261600 261600]], Phenylketonuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=261600 261600]]
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Known disease associated with this structure: Phenylketonuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=261600 261600]], Hyperphenylalaninemia, mild OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=261600 261600]]
==About this Structure==
==About this Structure==
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[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Andersen, O A.]]
[[Category: Andersen, O A.]]
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[[Category: FE]]
 
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[[Category: HBI]]
 
[[Category: 13 alpha-helice]]
[[Category: 13 alpha-helice]]
[[Category: 6 beta-strand]]
[[Category: 6 beta-strand]]
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[[Category: ferric iron]]
[[Category: ferric iron]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:34:20 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:06:28 2008''

Revision as of 19:06, 30 March 2008


PDB ID 1lrm

Drag the structure with the mouse to rotate
, resolution 2.1Å
Ligands: ,
Gene: PAH (Homo sapiens)
Activity: Phenylalanine 4-monooxygenase, with EC number 1.14.16.1
Related: 1DMW, 1J8U, 1J8T, 1PAH, 2PAH, 1KW0


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal structure of binary complex of the catalytic domain of human phenylalanine hydroxylase with dihydrobiopterin (BH2)


Disease

Known disease associated with this structure: Phenylketonuria OMIM:[261600], Hyperphenylalaninemia, mild OMIM:[261600]

About this Structure

1LRM is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Sun Mar 30 22:06:28 2008

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