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3fbk
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fbk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fbk RCSB], [http://www.ebi.ac.uk/pdbsum/3fbk PDBsum], [http://www.topsan.org/Proteins/NESGC/3fbk TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fbk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fbk RCSB], [http://www.ebi.ac.uk/pdbsum/3fbk PDBsum], [http://www.topsan.org/Proteins/NESGC/3fbk TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RGS3_HUMAN RGS3_HUMAN]] Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.<ref>PMID:8602223</ref> <ref>PMID:9858594</ref> <ref>PMID:10749886</ref> <ref>PMID:11294858</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 17:35, 25 December 2014
Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A
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Categories: Homo sapiens | Acton, T B | Ciccosanti, C | Everett, J K | Foote, E L | Forouhar, F | Hunt, J F | Lew, S | Mao, L | Montelione, G T | Structural genomic | Nair, R | Rost, B | Seetharaman, J | Shastry, R | Tong, L | Xiao, R | All beta-sheet fold | Cell membrane | Membrane | Nesg | Nucleus | Phosphoprotein | PSI, Protein structure initiative | Signal transduction inhibitor | Signaling protein
