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3fay
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fay FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fay OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fay RCSB], [http://www.ebi.ac.uk/pdbsum/3fay PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fay FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fay OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fay RCSB], [http://www.ebi.ac.uk/pdbsum/3fay PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IQGA1_HUMAN IQGA1_HUMAN]] Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.<ref>PMID:15695813</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 23:04, 24 December 2014
Crystal structure of the GAP-related domain of IQGAP1
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