This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3f5w

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 7: Line 7:
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f5w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3f5w RCSB], [http://www.ebi.ac.uk/pdbsum/3f5w PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f5w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3f5w RCSB], [http://www.ebi.ac.uk/pdbsum/3f5w PDBsum]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI]] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 21: Line 23:
*[[Antibody|Antibody]]
*[[Antibody|Antibody]]
*[[Potassium Channel|Potassium Channel]]
*[[Potassium Channel|Potassium Channel]]
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Revision as of 22:35, 25 December 2014

KcsA Potassium channel in the open-inactivated state with 32 A opening at T112

3f5w, resolution 3.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools