Glycolate oxidase
From Proteopedia
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| - | + | <StructureSection load='1rdu' size='350' side='right' caption='Human α-defensin 1 (PDB entry [[2pm4]])' scene=''> | |
| - | + | == Function == | |
| - | + | '''Glycolate oxidase''' (GOX) catalyzes the conversion of (S)-2-hydroxy acid and molecular oxygen to 2-oxo acid and hydrogen peroxide. In higher plants, GOX catalyzes the oxidation of glycolate to glyoxylate. GOX is part of the glyoxylate and dicarboxylate metabolism and uses FMN as a cofactor. GOX catalyzes the first step in the utilization of glycolate as the sole source of carbon<ref>PMID:22286136</ref>. | |
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| - | '''Glycolate oxidase''' (GOX) catalyzes the conversion of (S)-2-hydroxy acid and molecular oxygen to 2-oxo acid and hydrogen peroxide. In higher plants, GOX catalyzes the oxidation of glycolate to glyoxylate. GOX is part of the glyoxylate and dicarboxylate metabolism and uses FMN as a cofactor. GOX catalyzes the first step in the utilization of glycolate as the sole source of carbon. | + | |
==3D structures of glycolate oxidase== | ==3D structures of glycolate oxidase== | ||
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**[[1tb3]] – rGOX3 – rat | **[[1tb3]] – rGOX3 – rat | ||
| - | * | + | *Glycolate oxidase complex |
**[[1al8]], [[1al7]] – sGOX + inhibitor<br /> | **[[1al8]], [[1al7]] – sGOX + inhibitor<br /> | ||
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**[[3giy]] – GOX1/(S)-mandelate dehydrogenase + MES – ''Pseudomonas putida'' | **[[3giy]] – GOX1/(S)-mandelate dehydrogenase + MES – ''Pseudomonas putida'' | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:15, 14 March 2016
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