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Interleukin receptor
From Proteopedia
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | '''Interleukin receptor type I''' | + | *'''Interleukin receptor type I''' |
*Interleukin-2 receptor | *Interleukin-2 receptor | ||
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**[[3tgx]] – hIL21R extracellular domain (mutant) + interleukin-21 | **[[3tgx]] – hIL21R extracellular domain (mutant) + interleukin-21 | ||
| - | '''Interleukin receptor type II''' | + | *'''Interleukin receptor type II''' |
*Interleukin-10 receptor | *Interleukin-10 receptor | ||
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**[[3og4]], [[3og6]] - hIL28R α subunit + interleukin-29<br /> | **[[3og4]], [[3og6]] - hIL28R α subunit + interleukin-29<br /> | ||
| - | '''Interleukin receptor of immunoglobulin family''' | + | *'''Interleukin receptor of immunoglobulin family''' |
*Interleukin-1 receptor (CD121a, CD121b) | *Interleukin-1 receptor (CD121a, CD121b) | ||
Revision as of 07:34, 30 November 2014
Template:STRUCTURE 2b5i Interleukin receptors (ILR) are cytokine receptor which are classified into type I, type II and . ILR type I are cell surface receptors which recognize cytokines with four α-helical strands. ILR type II are similar to type I but lack the former’s signature sequence: WXSWS. Interleukin-1 receptor belongs to the ILR of immunoglobulin family. IL1R contains two types. Type I (IL1R1) binds interleukin-1 transmitting its inflammatory effect. Interleukin-1 receptor type II (IL1R2) suppresses interleukin-1 activity. Another suppressor of IL1R activity is the interleukin-1 receptor antagonist (IL1R1A).
3D structures of interleukin receptor
Updated on 30-November-2014
