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Kinesin
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== Kinesin == | == Kinesin == | ||
| - | [[Kinesin|Kinesins]] are eukaryotic motor proteins which move along microtubules. Kinesin (KIF) is a dimer consisting of 2 heavy chains and two light chains. The heavy chain contains the globular motor domain (MD), flexible neck linker (FNL) and a long coiled-coil stalk which intertwines to form the dimer. The light chain (KLC) forms the tail region. The KLC contains a cargo binding domain which is called TPR (Tetratricopeptide repeat). The KIFs are named by their gene number. KIF contains a forkhead-associated domain (FHA) which is involved in phosphopeptide recognition. Kinesin protein in yeast is called '''Kar3'''. '''Eg5''' or '''KIF11''' is a kinesin ([[Kinesin-5]]) which participates in mitosis. '''KCBP''' is a '''Kinesin-like Calmodulin Binding Protein'''. '''NOD''' is a Drosophila chromosome-associated kinesin. | + | [[Kinesin|Kinesins]] are eukaryotic motor proteins which move along microtubules. Kinesin (KIF) is a dimer consisting of 2 heavy chains and two light chains. The heavy chain contains the globular motor domain (MD), flexible neck linker (FNL) and a long coiled-coil stalk which intertwines to form the dimer. The light chain (KLC) forms the tail region. The KLC contains a cargo binding domain which is called TPR (Tetratricopeptide repeat). The KIFs are named by their gene number. KIF contains a forkhead-associated domain (FHA) which is involved in phosphopeptide recognition. Kinesin protein in yeast is called '''Kar3'''. '''Eg5''' or '''KIF11''' is a kinesin ([[Kinesin-5]]) which participates in mitosis. '''KCBP''' is a '''Kinesin-like Calmodulin Binding Protein'''. '''NOD''' is a Drosophila chromosome-associated kinesin. See also [[CAP-Gly domain]]. |
== 3D Structures of Kinesin == | == 3D Structures of Kinesin == | ||
Revision as of 08:16, 31 January 2016
3D Structure of Kinesin
The image is a Crystal Structure of the Kif1A Motor Domain Before Mg Release (2zfi)
Kinesin
Kinesins are eukaryotic motor proteins which move along microtubules. Kinesin (KIF) is a dimer consisting of 2 heavy chains and two light chains. The heavy chain contains the globular motor domain (MD), flexible neck linker (FNL) and a long coiled-coil stalk which intertwines to form the dimer. The light chain (KLC) forms the tail region. The KLC contains a cargo binding domain which is called TPR (Tetratricopeptide repeat). The KIFs are named by their gene number. KIF contains a forkhead-associated domain (FHA) which is involved in phosphopeptide recognition. Kinesin protein in yeast is called Kar3. Eg5 or KIF11 is a kinesin (Kinesin-5) which participates in mitosis. KCBP is a Kinesin-like Calmodulin Binding Protein. NOD is a Drosophila chromosome-associated kinesin. See also CAP-Gly domain.
3D Structures of Kinesin
Updated on 31-January-2016
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