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Lactoperoxidase
From Proteopedia
| Line 19: | Line 19: | ||
**[[2r5l]] – gLPO + I – goat<br /> | **[[2r5l]] – gLPO + I – goat<br /> | ||
**[[3nak]] – gLPO + formate<br /> | **[[3nak]] – gLPO + formate<br /> | ||
| - | **[[4ig5]] – gLPO + | + | **[[4ig5]], [[4qyq]] – gLPO + antithyroid agent<br /> |
*Lactoperoxidase ternary complex | *Lactoperoxidase ternary complex | ||
| Line 70: | Line 70: | ||
**[[3sxv]] - gPLO + amitrole + SCN + I<br /> | **[[3sxv]] - gPLO + amitrole + SCN + I<br /> | ||
**[[3r5q]] - sPLO +tetrahydrofuran + SCN + I<br /> | **[[3r5q]] - sPLO +tetrahydrofuran + SCN + I<br /> | ||
| + | **[[4qjq]] - gPLO + octopamine + SCN + I<br /> | ||
| + | **[[4s0y]] - bLPO + butyl-triazole + SCN + I<br /> | ||
| + | **[[4y55]] - wbLPO + rhodanide + SCN + I<br /> | ||
| + | |||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 08:19, 3 May 2015
Lactoperoxidase (LPO) catalyzes the oxidation of thiocyanate, bromide and iodide using hydrogen peroxide. The short-lived oxidized intermediates of the reaction serve as potent bactericidal agents. LPO is used as an antimicrobial agent in milk and its products, in cosmetics, toothpaste and ophthalmic solutions. LPO is the second most abundant enzyme in milk. Heme is the cofactor of LPO. LPO contains a strongly-chelated calcium ion.
3D structures of lactoperoxidase
Updated on 03-May-2015
Proteopedia Page Contributors and Editors (what is this?)
Joel L. Sussman, Michal Harel, Alexander Berchansky, Jaime Prilusky
