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Metabotropic glutamate receptor

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*Metabotropic glutamate receptor 1
*Metabotropic glutamate receptor 1
-
**[[1ewt]], [[1ewv]] - rMGluR1 ligand-binding domain<br />
+
**[[1ewt]], [[1ewv]] - rMGluR1 LBD - rat<br />
-
**[[3ks9]] – hMGluR1 (mutant) + antagonist<br />
+
**[[3ks9]] – hMGluR1 (mutant) + antagonist - human<br />
**[[4or2]] - hMGluR1/cytochrome b526<br />
**[[4or2]] - hMGluR1/cytochrome b526<br />
-
**[[1isr]], [[1ewk]] – rMGluR1 ligand-binding domain + Glu<br />
+
**[[1isr]], [[1ewk]] – rMGluR1 LBD + Glu<br />
-
**[[1iss]] - rMGluR1 ligand-binding domain + antagonist<br />
+
**[[1iss]] - rMGluR1 LBD + antagonist<br />
 +
 
 +
*Metabotropic glutamate receptor 2
 +
 
 +
**[[4xas]], [[4xaq]] – hMGluR2 LBD + agonist<br />
*Metabotropic glutamate receptor 3
*Metabotropic glutamate receptor 3
-
**[[2e4u]] – hMGluR3 ligand-binding domain (mutant) + Glu<br />
+
**[[2e4u]] – rMGluR3 LBD (mutant) + Glu<br />
-
**[[2e4v]], [[2e4w]], [[2e4x]], [[2e4y]], [[2e4z]] - hMGluR3 ligand-binding domain (mutant) + agonist<br />
+
**[[2e4v]], [[2e4w]], [[2e4x]], [[2e4y]], [[2e4z]] - rMGluR3 LBD (mutant) + agonist<br />
**[[3sm9]] - hMGluR3 + antagonist<br />
**[[3sm9]] - hMGluR3 + antagonist<br />
 +
**[[4xar]] – hMGluR3 LBD + agonist<br />
*Metabotropic glutamate receptor 5
*Metabotropic glutamate receptor 5
-
**[[3lmk]] – hMGluR5 ligand-binding domain (mutant) + positive allosteric modulator + Glu<br />
+
**[[3lmk]] – hMGluR5 LBD (mutant) + positive allosteric modulator + Glu<br />
*Metabotropic glutamate receptor 7
*Metabotropic glutamate receptor 7
-
**[[3mq4]] – hMGluR7 ligand-binding domain + antagonist<br />
+
**[[3mq4]] – hMGluR7 LBD + antagonist<br />
}}
}}
==See Also==
==See Also==

Revision as of 08:51, 8 April 2015

Metabotropic glutamate receptors are glutamate receptors that activate ion channels indirectly through a signalling cascade involving G proteins. They are members of the large class of seven-transmembrane domain receptors, the G protein-coupled receptors.

Structure of the binding domain of the Metabotropic Glutamate Receptor, GluR1, bound to glutamateand gadolinium ions (1isr)

Drag the structure with the mouse to rotate

Articles in Proteopedia concerning Toll-like Receptors include:


3D structures of metabotropic glutamate receptor

Updated on 08-April-2015

See Also

Membrane Channels & Pumps
Ionotropic_Glutamate_Receptors
Alzheimer's Disease

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Wayne Decatur, Nikki Hunter

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