Mitogen-activated protein kinase
From Proteopedia
(Difference between revisions)
| Line 115: | Line 115: | ||
**[[1lez]] - mMAPK14+MKK3B<br /> | **[[1lez]] - mMAPK14+MKK3B<br /> | ||
| - | *MAPK | + | *MAPK Fus3 |
| - | **[[2f9g]], [[2b9f]] – yMAPK | + | **[[2f9g]], [[2b9f]] – yMAPK Fus3 – yeast<br /> |
| - | **[[2fa2]] – yMAPK | + | **[[2fa2]] – yMAPK Fus3 (mutant)<br /> |
| - | **[[2f49]] - yMAPK | + | **[[2f49]] - yMAPK Fus3 +STE5 peptide<br /> |
| - | **[[2b9h]], [[2b9i]] - yMAPK | + | **[[2b9h]], [[2b9i]] - yMAPK Fus3 (mutant)+MSG5 peptide<br /> |
| - | **[[2b9j]] - yMAPK | + | **[[2b9j]] - yMAPK Fus3 (mutant)+FAR1 peptide<br /> |
*MAPK | *MAPK | ||
Revision as of 09:49, 5 May 2015
Mitogen-activated protein kinase (MAPK) also known as Extracellular Signal-Regulated Kinase (ERK) are serine/threonine kinases which regulate various cellular activities in response to extracellular stimuli by mitogens, heat shock and more. MAPK is part of the MAPK cascade which consists of MAPK, MAP2K and MAP3K which are activated by phosphorylation.
- MAPK1 and MAPK3 are activated in response to growth factors.
- For MAPK2 representations see Michael Roberts/BIOL115/ERK2.
- MAPK6 is activated by phorbol esters.
- MAPK7 is activated by stress stimuli.
- MAPK8, MAPK9, MAPK10 (called also c-Jun N-terminal kinase 3 or JNK3), MAPK11, MAPK12, MAPK13, MAPK14 are stress-activated.
- MAPK11 (also called p38-β MAPK), MAPK12 (also called p38-γ MAPK), MAPK13 (also called p38-δ MAPK), MAPK14 (also called p38-α MAPK) belong to the class called p38 MAPK.
3D Structures of Mitogen-activated protein kinase
Updated on 05-May-2015
