Neurexin
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_3bod| PDB=3bod | SIZE=400| SCENE= |right|CAPTION=Mouse neurexin 1α LNS domain with Ca+2 ion ([[3bod]]) }} | {{STRUCTURE_3bod| PDB=3bod | SIZE=400| SCENE= |right|CAPTION=Mouse neurexin 1α LNS domain with Ca+2 ion ([[3bod]]) }} | ||
| - | [[Neurexin|Neurexins]] (NRXN) are a family of presynaptic proteins which bind to the postsynaptic [[Neuroligin]] (NLGN) to form a complex which attaches neurons. The NRXN family contains 4 members which are numbered 1 to 4. The NRXN-α contains 6 homologous LNS domains while the NRXN-β contains only LNS6 | + | [[Neurexin|Neurexins]] (NRXN) are a family of presynaptic proteins which bind to the postsynaptic [[Neuroligin]] (NLGN) to form a complex which attaches neurons. The NRXN family contains 4 members which are numbered 1 to 4<ref>PMID:12796785</ref>. The NRXN-α contains 6 homologous LNS domains while the NRXN-β contains only LNS6. |
| - | + | See: [[Neurodevelopmental Disorders]]<br /> | |
| + | [[Neuroligin-Neurexin Interaction]] | ||
== 3D Structures of Neurexin == | == 3D Structures of Neurexin == | ||
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**[[3vkf]] - bNRXN-1β LNS domain+rNLGN-1 cholinesterase domain | **[[3vkf]] - bNRXN-1β LNS domain+rNLGN-1 cholinesterase domain | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:36, 8 May 2016
Neurexins (NRXN) are a family of presynaptic proteins which bind to the postsynaptic Neuroligin (NLGN) to form a complex which attaches neurons. The NRXN family contains 4 members which are numbered 1 to 4[1]. The NRXN-α contains 6 homologous LNS domains while the NRXN-β contains only LNS6.
See: Neurodevelopmental Disorders
Neuroligin-Neurexin Interaction
3D Structures of Neurexin
08-May-2016
References
- ↑ Dean C, Scholl FG, Choih J, DeMaria S, Berger J, Isacoff E, Scheiffele P. Neurexin mediates the assembly of presynaptic terminals. Nat Neurosci. 2003 Jul;6(7):708-16. PMID:12796785 doi:http://dx.doi.org/10.1038/nn1074
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