Pantothenate kinase
From Proteopedia
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**[[2ews]] - SaPanK + ANP – ''Staphylococcus aureus''<br /> | **[[2ews]] - SaPanK + ANP – ''Staphylococcus aureus''<br /> | ||
- | **[[4nb4]] - SaPanK + ADP + | + | **[[4nb4]], [[4m7x]], [[4m7y]] - SaPanK + ADP + pantothenate derivative<br /> |
*'''PanK III''' | *'''PanK III''' |
Revision as of 10:33, 7 May 2015
Pantothenate kinase (PanK) phosphorylates pantothenate (vitamin B5) (PAU) to form 4’-phosphopantothenate (PPT) using ATP as phosphate source. This is the first step in coenzyme A biosynthesis. PanK is regulated by feedback inhibition by CoA and its thioesters. Three types of PanK are known. PanK I found in bacteria; PanK II found mostly in eukaryotes; PanK III found in bacteria and known as CoaX.
3D structures of pantothenate kinase
Updated on 07-May-2015