Pantothenate kinase

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**[[2ews]] - SaPanK + ANP – ''Staphylococcus aureus''<br />
**[[2ews]] - SaPanK + ANP – ''Staphylococcus aureus''<br />
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**[[4nb4]] - SaPanK + ADP + pantothenamide<br />
+
**[[4nb4]], [[4m7x]], [[4m7y]] - SaPanK + ADP + pantothenate derivative<br />
*'''PanK III'''
*'''PanK III'''

Revision as of 10:33, 7 May 2015

Template:STRUCTURE 2f9w

Pantothenate kinase (PanK) phosphorylates pantothenate (vitamin B5) (PAU) to form 4’-phosphopantothenate (PPT) using ATP as phosphate source. This is the first step in coenzyme A biosynthesis. PanK is regulated by feedback inhibition by CoA and its thioesters. Three types of PanK are known. PanK I found in bacteria; PanK II found mostly in eukaryotes; PanK III found in bacteria and known as CoaX.

3D structures of pantothenate kinase

Updated on 07-May-2015

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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