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Hp is a class I human pathogen that can survive and colonize under acidic conditions of human stomach, prolonged exposure to which can result in gastric cancers. It requires two nickel dependent enzymes - Urease and NiFe-H2ase, to colonize and survive in acidic human stomach. Essentially, the Ni-metallochaperone, UreE is required for the maturation of Urease, which catalyzes the conversion of urea to ammonia and carbamate. | Hp is a class I human pathogen that can survive and colonize under acidic conditions of human stomach, prolonged exposure to which can result in gastric cancers. It requires two nickel dependent enzymes - Urease and NiFe-H2ase, to colonize and survive in acidic human stomach. Essentially, the Ni-metallochaperone, UreE is required for the maturation of Urease, which catalyzes the conversion of urea to ammonia and carbamate. | ||
== Function == | == Function == | ||
| - | + | UreE delivers Nickel to urease. | |
== Disease == | == Disease == | ||
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== Headline text == | == Headline text == | ||
| - | In the [http://www.umass.edu Maroney] | ||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
Revision as of 16:55, 2 December 2014
UreE: A Nickel Metallochaperone for Urease
Introduction
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References
[http://]
