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4wh8

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==Crystal Structure of HCV NS3/4A protease in complex with an Asunaprevir P1-P3 macrocyclic analog.==
==Crystal Structure of HCV NS3/4A protease in complex with an Asunaprevir P1-P3 macrocyclic analog.==
<StructureSection load='4wh8' size='340' side='right' caption='[[4wh8]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4wh8' size='340' side='right' caption='[[4wh8]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3M7:TERT-BUTYL+[(2R,6S,12Z,13AS,14AR,16AS)-2-[(7-CHLORO-4-METHOXYISOQUINOLIN-1-YL)OXY]-14A-{[CYCLOPROPYL(DIHYDROXY)-LAMBDA~4~-SULFANYL]CARBAMOYL}-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-6-YL]CARBAMATE'>3M7</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3M7:TERT-BUTYL+[(2R,6S,12Z,13AS,14AR,16AS)-2-[(7-CHLORO-4-METHOXYISOQUINOLIN-1-YL)OXY]-14A-{[CYCLOPROPYL(DIHYDROXY)-LAMBDA~4~-SULFANYL]CARBAMOYL}-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-6-YL]CARBAMATE'>3M7</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wh6|4wh6]], [[4wf8|4wf8]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wh6|4wh6]], [[4wf8|4wf8]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wh8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wh8 RCSB], [http://www.ebi.ac.uk/pdbsum/4wh8 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wh8 OCA], [http://pdbe.org/4wh8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wh8 RCSB], [http://www.ebi.ac.uk/pdbsum/4wh8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wh8 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4wh8" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>

Revision as of 00:22, 26 January 2017

Crystal Structure of HCV NS3/4A protease in complex with an Asunaprevir P1-P3 macrocyclic analog.

4wh8, resolution 2.70Å

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