4uqg
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uqg RCSB], [http://www.ebi.ac.uk/pdbsum/4uqg PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uqg RCSB], [http://www.ebi.ac.uk/pdbsum/4uqg PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | We report the development of a new heterobase that is held together through reversible bonding. The so-formed cross-link adds strong stabilization to the DNA duplex. Despite this, the cross-link opens and closes through reversible imine bonding. Moreover, even enzymatic incorporation of the cross-link is possible. The new principle can be used to stabilize DNA duplexes and nanostructures that otherwise require high salt concentrations, which may hinder biological applications. | ||
| + | |||
| + | "Post-It" Type Connected DNA Created with a Reversible Covalent Cross-Link.,Tomas-Gamasa M, Serdjukow S, Su M, Muller M, Carell T Angew Chem Int Ed Engl. 2014 Nov 28. doi: 10.1002/anie.201407854. PMID:25446281<ref>PMID:25446281</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 12:20, 10 December 2014
A new bio-isosteric base pair based on reversible bonding
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