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3gbx
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gbx RCSB], [http://www.ebi.ac.uk/pdbsum/3gbx PDBsum], [http://www.topsan.org/Proteins/CSGID/3gbx TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gbx RCSB], [http://www.ebi.ac.uk/pdbsum/3gbx PDBsum], [http://www.topsan.org/Proteins/CSGID/3gbx TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLYA_SALTY GLYA_SALTY]] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 14:52, 25 December 2014
Serine hydroxymethyltransferase from Salmonella typhimurium
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Categories: Glycine hydroxymethyltransferase | Salmonella enterica subsp. enterica serovar typhimurium | Anderson, W F | Structural genomic | Joachimiak, A | Nocek, B | Osipiuk, J | Stam, J | Zhou, M | Csgid | Idp01011 | One-carbon metabolism | Pyridoxal phosphate | Salmonella typhimurium | Serine hydroxymethyltransferase | Transferase
