1mem
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
|PDB= 1mem |SIZE=350|CAPTION= <scene name='initialview01'>1mem</scene>, resolution 1.8Å | |PDB= 1mem |SIZE=350|CAPTION= <scene name='initialview01'>1mem</scene>, resolution 1.8Å | ||
|SITE= <scene name='pdbsite=CAT:Description+Not+Provided'>CAT</scene> | |SITE= <scene name='pdbsite=CAT:Description+Not+Provided'>CAT</scene> | ||
| - | |LIGAND= <scene name='pdbligand=BZP:N1-CARBOXYPIPERAZINE'>BZP</scene> | + | |LIGAND= <scene name='pdbligand=BNS:HYDROSULFONYLBENZENE'>BNS</scene>, <scene name='pdbligand=BZP:N1-CARBOXYPIPERAZINE'>BZP</scene>, <scene name='pdbligand=NFP:3-AMINO-5-PHENYLPENTANE'>NFP</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mem OCA], [http://www.ebi.ac.uk/pdbsum/1mem PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1mem RCSB]</span> | ||
}} | }} | ||
'''CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR''' | '''CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Pycnodysostosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601105 601105]] | ||
==About this Structure== | ==About this Structure== | ||
| Line 24: | Line 24: | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Mcgrath, M E.]] | [[Category: Mcgrath, M E.]] | ||
| - | [[Category: BNS]] | ||
| - | [[Category: BZP]] | ||
[[Category: complex (hydrolase/inhibitor)]] | [[Category: complex (hydrolase/inhibitor)]] | ||
[[Category: cysteine]] | [[Category: cysteine]] | ||
| Line 33: | Line 31: | ||
[[Category: protease]] | [[Category: protease]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:15:11 2008'' |
Revision as of 19:15, 30 March 2008
| |||||||
| , resolution 1.8Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | , , | ||||||
| Activity: | Cathepsin K, with EC number 3.4.22.38 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR
About this Structure
1MEM is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Crystal structure of human cathepsin K complexed with a potent inhibitor., McGrath ME, Klaus JL, Barnes MG, Bromme D, Nat Struct Biol. 1997 Feb;4(2):105-9. PMID:9033587
Page seeded by OCA on Sun Mar 30 22:15:11 2008
