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3gdi
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gdi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gdi RCSB], [http://www.ebi.ac.uk/pdbsum/3gdi PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gdi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gdi RCSB], [http://www.ebi.ac.uk/pdbsum/3gdi PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PER2_MOUSE PER2_MOUSE]] Component of the circadian clock mechanism which is essential for generating circadian rhythms. Negative element in the circadian transcriptional loop. Influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. Negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation.<ref>PMID:10428031</ref> <ref>PMID:17310242</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 19:01, 24 December 2014
Mammalian Clock Protein mPER2 - Crystal Struture of a PAS Domain Fragment
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