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Protein phosphatase

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*Protein phosphatase 1A
*Protein phosphatase 1A
-
**[[3fxj]], [[3fxk]], [[3fxl]], [[3fxm]], [[3fxo]] – hPP1A + Mn – human<br />
+
**[[3fxj]], [[3fxk]], [[3fxl]], [[3fxm]], [[3fxo]], [[4ra2]] – hPP1A + Mn – human<br />
**[[4da1]] – hPP1K + Mn<br />
**[[4da1]] – hPP1K + Mn<br />
-
**[[1jk7]], [[1u32]], [[2bcd]], [[2bdx]], [[3e7a]], [[3e7b]] – hPP1 catalytic subunit + tumor-inducing toxin<br />
 
-
**[[1fjm]] – PP1 + tumor-inducing toxin - rabbit<br />
 
-
**[[3egg]] – hPP1 catalytic subunit + spinophilin<br />
 
-
**[[3hvq]] – hPP1 catalytic subunit + neuroabin<br />
 
**[[3n5u]] – hPP1A catalytic subunit + retinoblastoma-associated protein<br />
**[[3n5u]] – hPP1A catalytic subunit + retinoblastoma-associated protein<br />
**[[3v4y]] – hPP1A catalytic subunit + PP1 nuclear inhibitor<br />
**[[3v4y]] – hPP1A catalytic subunit + PP1 nuclear inhibitor<br />
**[[4g9j]] – hPP1A catalytic subunit + peptide<br />
**[[4g9j]] – hPP1A catalytic subunit + peptide<br />
-
**[[3egh]] – hPP1 catalytic subunit + spinophilin + toxin<br />
 
-
**[[1it6]] – hPP1 catalytic subunit + calyculin<br />
 
-
**[[1s70]] – hPP1 catalytic subunit (mutant) + smooth muscle myosin phosphatase<br />
 
-
**[[2o8a]], [[2o8g]] – PP1C catalytic subunit + inhibitor - rat<br />
 
**[[2rlt]] – PP1 regulatory subunit – pig - NMR<br />
**[[2rlt]] – PP1 regulatory subunit – pig - NMR<br />
*Protein phosphatase 2A
*Protein phosphatase 2A
-
**[[1b3u]], [[2ixm]], [[2jak]], [[2g62]] – hPP2A regulatory subunit <br />
+
**[[1b3u]], [[2g62]] – hPP2A regulatory subunit <br />
-
**[[2pkg]] – hPP2A regulatory subunit + small T antigen<br />
+
**[[2ie3]], [[2ie4]], [[2npp]], [[2nyl]], [[2nym]] – hPP2A catalytic + regulatory subunit + tumor-inducing toxin<br />
-
**[[2pf4]] – PP2A regulatory subunit + small T antigen - mouse<br />
+
-
**[[2ie3]], [[2ie4]], [[2npp]], [[2nyl]], [[2nym]], [[2iae]], [[3dw8]], [[3k7v]], [[3k7w]] – hPP2A catalytic + regulatory subunit + tumor-inducing toxin<br />
+
-
**[[3fga]] – hPP2C catalytic + regulatory subunit + tumor-inducing toxin + Sgo<br />
+
**[[3c5w]] – hPP2A catalytic + regulatory subunit + PP2A-specific methyltransferase<br />
**[[3c5w]] – hPP2A catalytic + regulatory subunit + PP2A-specific methyltransferase<br />
-
**[[3p71]] – hPP2A catalytic subunit + leucine carboxyl methyltransferase<br />
 
*Protein phosphatase 2C
*Protein phosphatase 2C
-
**[[1a6q]] – hPP2C <br />
 
**[[2iq1]] – hPP2C κ <br />
**[[2iq1]] – hPP2C κ <br />
-
**[[2p8e]] – hPP2C β<br />
 
-
**[[2cm1]] – PP2C + Mn – ''Mycobacterium tuberculosis''<br />
 
**[[3d8k]] – PP2C – ''Toxoplasma gondii''<br />
**[[3d8k]] – PP2C – ''Toxoplasma gondii''<br />
-
**[[3jrq]], [[3kdj]], [[3nmn]] – AtPP2C + Pyl1 – ''Arabidopsis thaliana''<br />
+
**[[3jrq]], [[3nmn]] – AtPP2C + Pyl1 – ''Arabidopsis thaliana''<br />
**[[3nmt]], [[3kb3]], [[3nmv]], [[3ujl]] – AtPP2C + Pyl2<br />
**[[3nmt]], [[3kb3]], [[3nmv]], [[3ujl]] – AtPP2C + Pyl2<br />
**[[4la7]], [[4lg5]], [4lga]], [[4lgb]] – AtPP2C + Pyl2 + ligand<br />
**[[4la7]], [[4lg5]], [4lga]], [[4lgb]] – AtPP2C + Pyl2 + ligand<br />
Line 53: Line 38:
**[[3rt0]] – AtPP2C (mutant) + Pyl10<br />
**[[3rt0]] – AtPP2C (mutant) + Pyl10<br />
**[[4n0g]] – AtPP2C + Pyl13<br />
**[[4n0g]] – AtPP2C + Pyl13<br />
-
**[[3qn1]], [[3zvu]] – AtPP2C + Pyr1<br />
+
**[[3qn1]], [[3zvu]], [[4wvo]] – AtPP2C + Pyr1<br />
-
**[[3ujg]] – AtPP2C + SNRK2<br />
+
**[[3ujk]] – AtPP2C <br />
**[[3ujk]] – AtPP2C <br />
 +
**[[4yzg]] – AtPP2C (mutant) <br />
 +
**[[4yzh]] – AtPP2C (mutant) + chlorophyll-binding protein peptide<br />
-
*Protein phosphatase 5
 
- 
-
**[[1s95]] – hPP5 catalytic domain <br />
 
-
**[[2g62]] – hPP5 <br />
 
-
**[[2bug]] – hPP5 tetratricopeptide domain + Hsp90 peptide<br />
 
-
**[[3h60]] – hPP5 catalytic domain + Mn<br />
 
-
**[[3h61]], [[3h62]], [[3h63]], [[3h64]] – hPP5 catalytic domain + Mn + inhibitor<br />
 
-
**[[3h66]] – hPP5 catalytic domain + Zn <br />
 
-
**[[3h67]], [[3h68]], [[3h69]] – hPP5 catalytic domain + Zn + inhibitor<br />
 
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:55, 21 May 2015

Template:STRUCTURE 3k7v

Protein phosphatases (PP) regular protein phosphorylation and thus are key in intracellular signal transduction processes.

  • PP1 is a serine/threonine phosphatase.
  • PP2A targets proteins in the oncogenic signaling pathways. For PP2A see also HEAT Repeat.
  • PP2C are Mg/Mn- dependent and are essential for the regulation of cell cycle and stress signaling pathways.
  • PP4 regulates a variety of cellular functions.
  • PP5 is activated by lipids and is involved in signal transduction.

3D Structures of protein phosphatase

Updated on 21-May-2015

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