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Purine repressor

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<StructureSection load='1qp4' size='350' side='right' caption='Structure of purine processor complex with DNA (green) and hypoxanthine (PDB entry [[1qp4]])' scene=''>
<StructureSection load='1qp4' size='350' side='right' caption='Structure of purine processor complex with DNA (green) and hypoxanthine (PDB entry [[1qp4]])' scene=''>
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== Function ==
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'''Purine repressor''' (PurR) is a member of the lac repressor family. PurP binds DNA via a highly conserved helix-turn-helix at the N terminal (DBD). PurP contains a co-repressor binding domain as well (CBD). PurP binds to a 16-bp operator sequence and co-regulates genes which are involved in the biosynthesis of purine and pyrimidine nucleotides.
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'''Purine repressor''' (PurR) is a member of the lac repressor family. PurP binds DNA via a highly conserved helix-turn-helix at the N terminal (DBD). PurP contains a co-repressor binding domain as well (CBD). PurP binds to a 16-bp operator sequence and co-regulates genes which are involved in the biosynthesis of purine and pyrimidine nucleotides<ref>PMID:1971621</ref>.
</StructureSection>
</StructureSection>
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**[[1zay]] - EcPurR + DNA + hypoxanthine + di-imino-purine<br />
**[[1zay]] - EcPurR + DNA + hypoxanthine + di-imino-purine<br />
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}}
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:32, 31 July 2016

Structure of purine processor complex with DNA (green) and hypoxanthine (PDB entry 1qp4)

Drag the structure with the mouse to rotate

3D structures of purine repressor

Updated on 31-July-2016

References

  1. ↑ Wilson HR, Turnbough CL Jr. Role of the purine repressor in the regulation of pyrimidine gene expression in Escherichia coli K-12. J Bacteriol. 1990 Jun;172(6):3208-13. PMID:1971621

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