Response regulator

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Line 43: Line 43:
**[[1nxo]], [[1nxp]], [[1nxs]], [[1nxt]], [[1nxv]], [[1nxw]], [[1nxx]] – SpMicArec receiver domain – ''Streptococcus pneumonia''<br/ >
**[[1nxo]], [[1nxp]], [[1nxs]], [[1nxt]], [[1nxv]], [[1nxw]], [[1nxx]] – SpMicArec receiver domain – ''Streptococcus pneumonia''<br/ >
**[[2gwr]] - MtMtrA – ''Mycobacterium tuberculosis''<br/ >
**[[2gwr]] - MtMtrA – ''Mycobacterium tuberculosis''<br/ >
-
**[[2hwv]] – VicR C terminal – ''Enterococcus faecalis''<br/ >
+
**[[2hwv]] – EfVicR C terminal – ''Enterococcus faecalis''<br/ >
**[[2qsj]] – LuxR – ''Silicibbacter pomeroyi''<br/ >
**[[2qsj]] – LuxR – ''Silicibbacter pomeroyi''<br/ >
**[[3cnb]], [[3eqz]] – MerR receiver domain – ''Colwellia psychrerythraea''<br/ >
**[[3cnb]], [[3eqz]] – MerR receiver domain – ''Colwellia psychrerythraea''<br/ >
Line 53: Line 53:
**[[3q9v]] - DrRR C terminal<br />
**[[3q9v]] - DrRR C terminal<br />
**[[3rjp]] - RR DNA -binding domain – ''Streptococcus pyogenes''<br />
**[[3rjp]] - RR DNA -binding domain – ''Streptococcus pyogenes''<br />
 +
**[[2a9r]] – SpRR N terminal + phosphate + Mg
*Cyanobacterial phytochrome response regulator
*Cyanobacterial phytochrome response regulator
Line 132: Line 133:
*Two-component response regulator
*Two-component response regulator
-
**[[2lpm]] – SmRR
+
**[[2lpm]] – SmRR <br />
 +
**[[2m98]] – RR – ''Sinorhizobium meliloti''<br />
 +
**[[4q7e]] – RR receiver domain – ''Leptospira biflexa''<br />
 +
**[[2qr3]] – RR N terminal – ''Bacteroides fragilis''<br />
 +
**[[2qzj]] – RR – ''Clostridium difficile''<br />
 +
**[[3cz5]] – RR – ''Aurantimonas''
-
*Unspecified response regulator receiver domain
+
*response regulator receiver domain protein
-
**[[2a9o]], [[2a9p]], [[2a9q]] – SpRR + Mn + BeF3<BR/ >
+
**[[4wsz]] – EfRR<br />
-
**[[2a9r]] – SpRR + phosphate + Mg<br/ >
+
-
**[[2pln]] – HP1043 – ''Helicobacter pylori''<br/ >
+
-
**[[2qr3]] – RR – ''Bacteroides fragilis''<br/ >
+
-
**[[2qxy]] – TmRR <br/ >
+
-
**[[2qzj]] – RR – ''Clostridium difficile''<br/ >
+
-
**[[3kht]] – RR – ''Hahella chejuensis''<br/ >
+
**[[3c3m]] – RR – ''Methanoculleus marisnigri''<br/ >
**[[3c3m]] – RR – ''Methanoculleus marisnigri''<br/ >
-
**[[3cz5]] – RR – ''Aurantimonas''<br/ >
 
**[[3heb]] - RR – ''Rhodospirillum rubrum''<br/ >
**[[3heb]] - RR – ''Rhodospirillum rubrum''<br/ >
**[[3lte]] – RR – ''Bermanella marisrubri''<br/ >
**[[3lte]] – RR – ''Bermanella marisrubri''<br/ >
**[[3jte]], [[3lua]] – RR – ''Clostridium thermocellum''<br />
**[[3jte]], [[3lua]] – RR – ''Clostridium thermocellum''<br />
-
**[[4e7o]] – SpRR<br />
+
**[[4wt0]] – EfRR DNA-binding domain (mutant)<br />
-
**[[4e7p]] – SpRR + BeF3<br />
+
**[[4wu4]], [[4wuh]], [[4wul]] – EfRR DNA-binding domain + DNA<br />
-
**[[2b4a]] – RR Bh3024 – ''Bacillus halodurans''<br />
+
**[[4xlt]] – RR – ''Dyadobacter fermentans''<br />
*Unspecified response regulator
*Unspecified response regulator
Line 157: Line 156:
**[[3a0u]], [[3a10]] – TmTrrA + Mg + BeF3<BR/ >
**[[3a0u]], [[3a10]] – TmTrrA + Mg + BeF3<BR/ >
**[[2qvg]] – RR – ''Legionella pneumophila''<br/ >
**[[2qvg]] – RR – ''Legionella pneumophila''<br/ >
-
**[[3gl9]] - TmRR<br/ >
+
**[[3gl9]], [[2qxy]], [[4ja2]] - TmRR<br/ >
**[[4hye]] – SpRR<br />
**[[4hye]] – SpRR<br />
**[[2zay]] – RR – ''Desulfuromonas acetoxidans''<br/ >
**[[2zay]] – RR – ''Desulfuromonas acetoxidans''<br/ >
Line 181: Line 180:
**[[4ml3]], [[4mld]] – SpRR Rec domain (mutant)<br />
**[[4ml3]], [[4mld]] – SpRR Rec domain (mutant)<br />
**[[4cbv]] – SpRR (mutant)<br />
**[[4cbv]] – SpRR (mutant)<br />
 +
**[[2a9o]], [[2a9p]], [[2a9q]] – SpRR + Mn + BeF3<br />
 +
**[[2pln]] – HP1043 – ''Helicobacter pylori''<br />
 +
**[[3kht]] – RR – ''Hahella chejuensis''
*Response regulator complex with histidine kinase
*Response regulator complex with histidine kinase

Revision as of 10:58, 26 May 2015

Template:STRUCTURE 1kgs

Response regulators (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal shich is the signal receiving domain and C terminal which is the DNA-binding domain. RR CheY is a chemotaxis response regulator in bacteria. RR Spo0 is the sporulation response regulator. For details see:
For PleD:

For PhoP:

For photosynthetic apparatus RR:

For WspR RR:

3D Structures of response regulator

Updated on 26-May-2015

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky, Jaime Prilusky

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