3gng

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [http://www.ebi.ac.uk/pdbsum/3gng PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [http://www.ebi.ac.uk/pdbsum/3gng PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MVP_MOUSE MVP_MOUSE]] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 18:35, 24 December 2014

P21B crystal structure of R1-R7 of Murine MVP

3gng, resolution 3.00Å

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