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3ggy
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ggy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ggy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ggy RCSB], [http://www.ebi.ac.uk/pdbsum/3ggy PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ggy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ggy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ggy RCSB], [http://www.ebi.ac.uk/pdbsum/3ggy PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IST1_YEAST IST1_YEAST]] Involved in a late step in sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. The lumenal sequestrated membrane proteins are targeted into the vacuole after fusion of the endosome with the vacuole. Regulates the recruitment of VPS4 to the ESCRT-III complex, probably in conjunction with DID2, and VPS4 catalyzes the disassembly of the ESCRT-III complex.<ref>PMID:18032582</ref> <ref>PMID:18032584</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 01:21, 25 December 2014
Crystal Structure of S.cerevisiae Ist1 N-terminal domain
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