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3nde

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==Crystal Structure of BlaC-E166A covalently bound with Cephalotin==
==Crystal Structure of BlaC-E166A covalently bound with Cephalotin==
<StructureSection load='3nde' size='340' side='right' caption='[[3nde]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3nde' size='340' side='right' caption='[[3nde]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3nde]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NDE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NDE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3nde]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NDE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NDE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9EP:(2R)-5-[(ACETYLOXY)METHYL]-2-{(1R)-2-OXO-1-[(THIOPHEN-2-YLACETYL)AMINO]ETHYL}-3,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>9EP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9EP:(2R)-5-[(ACETYLOXY)METHYL]-2-{(1R)-2-OXO-1-[(THIOPHEN-2-YLACETYL)AMINO]ETHYL}-3,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>9EP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nde OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nde RCSB], [http://www.ebi.ac.uk/pdbsum/3nde PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nde OCA], [http://pdbe.org/3nde PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nde RCSB], [http://www.ebi.ac.uk/pdbsum/3nde PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nde ProSAT]</span></td></tr>
</table>
</table>
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</StructureSection>
</StructureSection>
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
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[[Category: Mycobacterium tuberculosis]]
 
[[Category: Blanchard, J S]]
[[Category: Blanchard, J S]]
[[Category: Tremblay, L W]]
[[Category: Tremblay, L W]]

Revision as of 04:03, 10 December 2016

Crystal Structure of BlaC-E166A covalently bound with Cephalotin

3nde, resolution 1.70Å

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