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3q2g
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q2g RCSB], [http://www.ebi.ac.uk/pdbsum/3q2g PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q2g RCSB], [http://www.ebi.ac.uk/pdbsum/3q2g PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ATS1_HUMAN ATS1_HUMAN]] Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.<ref>PMID:10438512</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 15:15, 25 December 2014
Adamts1 in complex with a novel N-hydroxyformamide inhibitors
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