1n7s
From Proteopedia
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|PDB= 1n7s |SIZE=350|CAPTION= <scene name='initialview01'>1n7s</scene>, resolution 1.45Å | |PDB= 1n7s |SIZE=350|CAPTION= <scene name='initialview01'>1n7s</scene>, resolution 1.45Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> | + | |LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n7s OCA], [http://www.ebi.ac.uk/pdbsum/1n7s PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1n7s RCSB]</span> | ||
}} | }} | ||
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[[Category: Brunger, A T.]] | [[Category: Brunger, A T.]] | ||
[[Category: Ernst, J A.]] | [[Category: Ernst, J A.]] | ||
| - | [[Category: CA]] | ||
| - | [[Category: MPD]] | ||
[[Category: four helix bundle]] | [[Category: four helix bundle]] | ||
[[Category: neuronal snare protein complex]] | [[Category: neuronal snare protein complex]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:26:33 2008'' |
Revision as of 19:26, 30 March 2008
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| , resolution 1.45Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
High Resolution Structure of a Truncated Neuronal SNARE Complex
Overview
The structure of a truncated SNARE complex has been solved to 1.4-A resolution revealing a stabilizing salt bridge, sites of hydration, and conformational variability of the ionic central layer that were not observed in a previously published structure at 2.4-A resolution (Sutton, R. B., Fasshauer, D., Jahn, R., and Brunger, A. T. (1998) Nature 395, 347-353). The truncated complex lacks residues involved in phospholipid binding and denatures at a lower temperature than longer complexes as assessed by SDS and circular dichroism thermal melts. The truncated SNARE complex is monomeric, and it retains binding to synaptotagmin I.
About this Structure
1N7S is a Protein complex structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complex., Ernst JA, Brunger AT, J Biol Chem. 2003 Mar 7;278(10):8630-6. Epub 2002 Dec 20. PMID:12496247
Page seeded by OCA on Sun Mar 30 22:26:33 2008
