3o16

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o16 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o16 RCSB], [http://www.ebi.ac.uk/pdbsum/3o16 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o16 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o16 RCSB], [http://www.ebi.ac.uk/pdbsum/3o16 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/THIE_BACSU THIE_BACSU]] Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Is also able to use the 2-methoxy analog MeO-HMP-PP, as substrate in vitro, but not the 2-trifluoromethyl analog CF(3)-HMP-PP.<ref>PMID:9139923</ref> <ref>PMID:11513588</ref>
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== References ==
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<references/>
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</StructureSection>
</StructureSection>

Revision as of 22:40, 24 December 2014

Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase K159A

3o16, resolution 2.10Å

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