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3nv2
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nv2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nv2 RCSB], [http://www.ebi.ac.uk/pdbsum/3nv2 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nv2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nv2 RCSB], [http://www.ebi.ac.uk/pdbsum/3nv2 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q53FQ0_HUMAN Q53FQ0_HUMAN]] Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant.<ref>PMID:16286920</ref> <ref>PMID:18005988</ref> <ref>PMID:18977853</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 03:12, 25 December 2014
Crystal structure of human galectin-9 C-terminal CRD in complex with N-acetyllactosamine
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