3qwh
From Proteopedia
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==Crystal structure of the 17beta-hydroxysteroid dehydrogenase from Cochliobolus lunatus in complex with NADPH and kaempferol== | ==Crystal structure of the 17beta-hydroxysteroid dehydrogenase from Cochliobolus lunatus in complex with NADPH and kaempferol== | ||
<StructureSection load='3qwh' size='340' side='right' caption='[[3qwh]], [[Resolution|resolution]] 2.62Å' scene=''> | <StructureSection load='3qwh' size='340' side='right' caption='[[3qwh]], [[Resolution|resolution]] 2.62Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3qwh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3qwh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Coclu Coclu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QWH FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KMP:3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE'>KMP</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KMP:3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE'>KMP</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3is3|3is3]], [[3itd|3itd]], [[3qwf|3qwf]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3is3|3is3]], [[3itd|3itd]], [[3qwf|3qwf]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">17HSDcl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5503 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">17HSDcl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5503 COCLU])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/17-beta-estradiol_17-dehydrogenase 17-beta-estradiol 17-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.62 1.1.1.62] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qwh RCSB], [http://www.ebi.ac.uk/pdbsum/3qwh PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwh OCA], [http://pdbe.org/3qwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3qwh RCSB], [http://www.ebi.ac.uk/pdbsum/3qwh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwh ProSAT]</span></td></tr> |
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: 17-beta-estradiol 17-dehydrogenase]] |
| - | [[Category: | + | [[Category: Coclu]] |
[[Category: Brunskole, M]] | [[Category: Brunskole, M]] | ||
[[Category: Cassetta, A]] | [[Category: Cassetta, A]] | ||
Revision as of 11:25, 10 December 2016
Crystal structure of the 17beta-hydroxysteroid dehydrogenase from Cochliobolus lunatus in complex with NADPH and kaempferol
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Categories: 17-beta-estradiol 17-dehydrogenase | Coclu | Brunskole, M | Cassetta, A | Krastanova, I | Kristan, K | Lamba, D | Rizner, T L | Stojan, J | 17beta-hydroxysteroid dehydrogenase | Cytosol | Flavonoid | Oxidoreductase-oxidoreductase inhibitor complex | Phytoestrogen | Rossmann fold | Short chain dehydrogenase/reductase
