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3snp

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3snp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3snp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3snp RCSB], [http://www.ebi.ac.uk/pdbsum/3snp PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3snp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3snp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3snp RCSB], [http://www.ebi.ac.uk/pdbsum/3snp PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ACOC_RABIT ACOC_RABIT]] Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding (By similarity). Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity).
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 18:12, 24 December 2014

Crystal structure analysis of iron regulatory protein 1 in complex with ferritin H IRE RNA

3snp, resolution 2.80Å

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