4fr8

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==Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin==
==Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin==
<StructureSection load='4fr8' size='340' side='right' caption='[[4fr8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4fr8' size='340' side='right' caption='[[4fr8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4fr8]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FR8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FR8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4fr8]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FR8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FR8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TNG:PROPANE-1,2,3-TRIYL+TRINITRATE'>TNG</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TNG:PROPANE-1,2,3-TRIYL+TRINITRATE'>TNG</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zum|1zum]], [[3n80|3n80]], [[3n81|3n81]], [[3n82|3n82]], [[3n83|3n83]], [[2onm|2onm]], [[3inl|3inl]], [[3sz9|3sz9]], [[2onn|2onn]], [[1o05|1o05]], [[2ono|2ono]], [[3inj|3inj]], [[1nzw|1nzw]], [[1nzx|1nzx]], [[1nzz|1nzz]], [[1o00|1o00]], [[1o01|1o01]], [[1o02|1o02]], [[1o04|1o04]], [[2onp|2onp]], [[2vle|2vle]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zum|1zum]], [[3n80|3n80]], [[3n81|3n81]], [[3n82|3n82]], [[3n83|3n83]], [[2onm|2onm]], [[3inl|3inl]], [[3sz9|3sz9]], [[2onn|2onn]], [[1o05|1o05]], [[2ono|2ono]], [[3inj|3inj]], [[1nzw|1nzw]], [[1nzx|1nzx]], [[1nzz|1nzz]], [[1o00|1o00]], [[1o01|1o01]], [[1o02|1o02]], [[1o04|1o04]], [[2onp|2onp]], [[2vle|2vle]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ALDH2, ALDM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ALDH2, ALDM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(NAD(+)) Aldehyde dehydrogenase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.3 1.2.1.3] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(NAD(+)) Aldehyde dehydrogenase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.3 1.2.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fr8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fr8 RCSB], [http://www.ebi.ac.uk/pdbsum/4fr8 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fr8 OCA], [http://pdbe.org/4fr8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fr8 RCSB], [http://www.ebi.ac.uk/pdbsum/4fr8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fr8 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4fr8" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Gruber, K]]
[[Category: Gruber, K]]
[[Category: Lang, B S]]
[[Category: Lang, B S]]

Revision as of 20:08, 15 December 2016

Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin

4fr8, resolution 2.20Å

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