4e74
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e74 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e74 RCSB], [http://www.ebi.ac.uk/pdbsum/4e74 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e74 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e74 RCSB], [http://www.ebi.ac.uk/pdbsum/4e74 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PLXA4_HUMAN PLXA4_HUMAN]] Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity). | ||
==See Also== | ==See Also== | ||
Revision as of 21:19, 25 December 2014
Crystal structure of the RHO GTPASE BINDING DOMAIN of Plexin A4A
| |||||||||||
Categories: Homo sapiens | Arrowsmith, C H | Bountra, C | Dong, A | Edwards, A M | Guan, X | Park, H | Structural genomic | Tempel, W | Tong, Y | Wang, H | Weigelt, J | Plexin | Rbd | Sgc | Signaling protein
