SAM-dependent methyltransferase
From Proteopedia
(Difference between revisions)
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**[[3bkx]] – SDM – ''Lactobacillus casei''<br /> | **[[3bkx]] – SDM – ''Lactobacillus casei''<br /> | ||
**[[3kr9]] – SpSDM – ''Streptococcus pneumonia''<br /> | **[[3kr9]] – SpSDM – ''Streptococcus pneumonia''<br /> | ||
| + | |||
| + | *SAM-dependent methyltransferase complex with SAM/SAH | ||
| + | |||
**[[3ku1]] – SpSDM + SAM<br /> | **[[3ku1]] – SpSDM + SAM<br /> | ||
**[[3lga]] – PaSDM + SAH – ''Pyrococcus abyssi''<br /> | **[[3lga]] – PaSDM + SAH – ''Pyrococcus abyssi''<br /> | ||
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**[[3ou7]] – SlSDM + SAM + phosphonic acid derivative<br /> | **[[3ou7]] – SlSDM + SAM + phosphonic acid derivative<br /> | ||
**[[3h2b]] – CgSDM + pyrophosphate + SAH<br /> | **[[3h2b]] – CgSDM + pyrophosphate + SAH<br /> | ||
| - | **[[1bc5]] – SDM + chemotaxis receptor peptide + SAH - ''Salmonella typhimurium'' | + | **[[1bc5]] – SDM + chemotaxis receptor peptide + SAH - ''Salmonella typhimurium''<br /> |
| + | **[[5bp7]] – SlSDM + SAH – ''Geobacter sulfurreducens''<br /> | ||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:28, 14 June 2015
SAM-dependent methyltransferase (SDM) utilizes the methyl donor S-adenosyl-L-methionine (SAM) as a cofactor to methylate proteins, small molecules, lipids and nucleic acids. SAM forms S-adenosyl-L-homocysteine (SAH) upon demethylation. About 120 members of the SDM family have been identified. They differ in their substrate specificity and the atom targeted for methylation (N, O, C, S). The core of the SDM fold contains alternating β strands and α helices. See also Molecular Playground/CheR.
3D structures of SAM-dependent methyltrasferase
Updated on 14-June-2015
